Of Fish, Fly, Worm, and Man : Lessons from Developmental Biology for Human Gene Function and Disease

Language: English

Published by Springer, 2012

3662042665 / 9783662042663

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Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH

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Druck auf Anfrage Neuware - Printed after ordering - The first complete genome sequence of a multicellular organism, Caenorhabditis elegans, has been determined recently. Several more will follow soon, among them the genome sequences of Drosophila melanogaster and the human. With these achievements, the stage is set for the next phase of 'large-scale' biology, the study of the function of genes and the interactions between their protein products. The aim of the Ernst Schering Research Foundation Workshop 29 was to discuss the contribution of research on model organisms which are particularly suited for genetic and biological research, to the understanding of gen eral principles of biology as well as the basis for human diseases. This area of research has not only unveiled the basic molecular mechanisms of development of higher organisms, but has also made major contri butions to the elucidation of complex signal transduction pathways that play crucial roles both in ontogeny and human diseases. Establishing the complete molecular anatomy of an organism is a demanding but rather well-defined task. However, compared to the technical and scientific challenges of large-scale sequencing and the bioinformatics analysis of complete genome data, the assignment of function to the genes of multicellular organisms may still seem like a fishing expedition, with no universal road to success. One approach is based on large-scale technologies. The use of mi croarrays for multiple gene expression analysis is one element in this effort, providing important information on the cell- or tissue-specific activation of genes over time.…

Seller Inventory # 9783662042663

Title
Of Fish, Fly, Worm, and Man : Lessons from Developmental Biology for Human Gene Function and Disease
Author
J. Krätzschmar
Publisher
Springer
Publication year
2012
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
3662042665
ISBN 13
9783662042663
Item weight
341 grams
Dimensions
210x148x15 mm

AHA-BUCH GmbH

Einbeck, Germany

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