Le dysfonctionnement cognitif dans le diab�te de type 2 est associ� � une diminution de la vitesse psychomotrice, de la fonction ex�cutive du lobe frontal, de la m�moire verbale, de la vitesse de traitement, de la motricit� complexe, de la m�moire de travail et du rappel imm�diat. Bien que le diab�te de type 2 soit associ� � plusieurs autres facteurs de risque vasculaire de d�mence, le diab�te lui-m�me a �t� consid�r� comme un facteur de risque ind�pendant de d�ficience cognitive et de d�mence. Il s'agit d'une �tude d'observation prospective visant � �valuer les fonctions cognitives des patients diab�tiques trait�s avec diff�rentes classes d'hypoglyc�miants oraux, avec ou sans comorbidit�s, dans le service de consultation externe de l'h�pital central gouvernemental de Nilgiris et dans divers centres de sant� tertiaires de Coimbatore. 400 patients ont �t� s�lectionn�s, dont 325 remplissaient les crit�res d'inclusion et d'exclusion. La pr�sente �tude a montr� que les patients prenant des inhibiteurs de la dipeptidyl peptidase-4 en association avec la metformine pr�sentaient un meilleur score cognitif global que les patients prenant des inhibiteurs de l'alpha glucosidase, des thiazolidinediones ou des sulfonylur�es en association avec la metformine.

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**Please note our transit times are from the date of dispatch.** We first started out as ?The Paperback Exchange,? a chain of physical bookstores where we would part exchange your beloved books for new stories to transport you to faraway places. However, as shopping started to evolve to online shops and marketplaces, we bid our stores goodbye to become ?PBShop.? This transition has only allowed us to blossom as we now ship thousands of titles to book lovers across the globe. We pride ourselves in being a community of local book lovers which allows our passion and devotion to shine in everything we do. In 2020 we not only celebrated our 20th birthday but our 1st birthday as being completely employee owned after becoming an E.O.T in September 2019. We are proud to be different and embrace standing apart on a book mountain by working from a virtual inventory which allows us to provide thousands of books that may be difficult to get for your bookshelf or your studies. Working with a number of different suppliers allows us to explore other avenues such as puzzles, sheet music and even stationery so we really do have something for everyone. Life is about being versatile in all realms of existence. If this is your first purchase with us, or you are a returning customer, we would like to welcome you to the PBShop family, for there is no friend as loyal as a book. We are a company who put our customers at the centre of everything we do as we understand the importance of reading because once you learn to read, you will forever be free. There are a whole lot of things in this world of ours that we are yet to explore, which is why we will forever inspire curious minds.

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