Formulation and Characterization of Aceclofenac Microsphere | Aceclofenac Microsphere
Sofiya Verma (u. a.)
ISBN 10: 3659202320 ISBN 13: 9783659202322
Published by LAP Lambert Academic Publishing, 2012
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preigu, Osnabrück, Germany
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Formulation and Characterization of Aceclofenac Microsphere | Aceclofenac Microsphere | Sofiya Verma (u. a.) | Taschenbuch | Englisch | LAP Lambert Academic Publishing | EAN 9783659202322 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu. Seller Inventory # 106341992
Synopsis:
The purpose of this research was to prepare and characterize Aceclofenac microsphere of guar gum polymer for the application of inflammation. Method: - The microsphere were prepared by using emulsification method using starch cross-linked agent and coating was done by solvent evaporation method with the pH sensitive eudragit S-100 polymers. Result:-The prepared microsphere were white, free flowing and spherical in shape. The drug-loaded microsphere showed entrapment efficiency and drug release was extended upto 6 to 8 h. The infrared spectra, differential scanning calorimetry thermographs spectra all showed the stable character of both the drugs in the drug-loaded microspheres and revealed the absence of drug-polymer interactions. Scanning electron microscopy study revealed that the microspheres were spherical and porous in nature. The stability study was conducted to conform the stability of prepared microsphere. In-vitro drug release study was performed in both simulated gastrointestinal fluid medium and rat cecal content of different pH. Conclusion:-The prepared Aceclofenac microsphere has the potential for delaying the release of drug.
About the Author: Sofiya Verma completed her M Pharmacy fromRajiv Gandhi Technical University Bhopal M.P.(India)Sofiya Verma having excellent academicsrecord. She is currently working as Asst. Professor at daksh institute of pharmaceutical science chhatarpur (M.P)
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Bibliographic Details
Title: Formulation and Characterization of ...
Publisher: LAP Lambert Academic Publishing
Publication Date: 2012
Binding: Taschenbuch
Condition: Neu