Formulation and Characterization of Diclofenac Sodium Gel : Diclofenac Sodium Novel Gel Formulation and it's Characterization

Language: English

Published by LAP LAMBERT Academic Publishing, 2023

6206167070 / 9786206167075

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Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH

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nach der Bestellung gedruckt Neuware - Printed after ordering - In this present study it can be concluded that topical gel formulations containing drug Diclofenac sodium were prepared with different concentration of gelling agents (carbopol-940/934/ HPMC 3K), which have shown an acceptable results in various evaluation studies. Gel was characterized on basis of various evaluation paeameters, All prepared gel showed acceptable physical properties concerning color, odour, consistency, uniformity, homogeneity, pH value, viscosity and spreadability. An in vitro drug release study was carried out using an egg membrane by using instrument franz's diffusion cell (dolphin).The results indicates that in over 24 hours of total study up to 90.12 % of diclofenac sodium drug is release through the membrane. According to the results obtained from this study, it was concluded that Diclofenac Sodium was successfully incorporated into the carbopol formulation to obtain a gel. F5 gel formulation showed good pH value, conductivity, viscosity, spreadability, and stability before and after the 12 days in the freeze-thaw cycle. Therefore, it was concluded that the formulation F5, could be very promising alternative for the topical or transdermal treatment.…

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Bibliographic details

Title
Formulation and Characterization of Diclofenac Sodium Gel : Diclofenac Sodium Novel Gel Formulation and it's Characterization
Author
Ritesh Limjhe
Publisher
LAP LAMBERT Academic Publishing
Publication year
2023
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
6206167070
ISBN 13
9786206167075
Item weight
131 grams
Dimensions
220x150x5 mm

AHA-BUCH GmbH

Einbeck, Germany

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