Formulation and Evaluation of Cephalexin Extended Release Tablet: Comparatively Study with Marketed Formulations

Sharma, Hemendra Kumar, Chaurasia, Sandhya, Vasireddy, Sunee

ISBN 10: 3848432633 / ISBN 13: 9783848432639

Published by LAP LAMBERT Academic Publishing, 2012

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Bibliographic Details

• Title: Formulation and Evaluation of Cephalexin Extended Release Tablet: Comparatively Study with Marketed Formulations
• Publisher: LAP LAMBERT Academic Publishing
• Publication Date: 2012
• Language: English
• ISBN 10: 3848432633
• ISBN 13: 9783848432639
• Binding: paperback
• Condition: Like New
• Book Type: book

About this title

Synopsis

In this study, controlled release matrix tablets containing cephelexin were prepared using HPMC15 cps and Eudragit L100 in different concentration by Direct compression method. Tablets were evaluated for physical properties,Hardness, friability, weight variation and In vitro dissolution study was carried on USP II apparetus (peddle type). The best formulations selected based on above parameters were subjected for Extend release study with use of different ratio of polymer as Eudragit and HPMC .The tablets with Eudragit were found to release drug for longer duration of time as compared to formulations containing HPMC. The drug release from the tablets was sufficiently sustained.

About the Author

Mr. Hemendra Kumar Sharma has obtained M. Pharm degree in Pharmaceutical Chemistry in 2011. Since he has published three international and ten national research article in reputed journals in field of analysis and he has also obtained scientific credit from international journal.