Formulation And Evaluation Of Multilayer Matrix Tablet

Sumedha Bansal

ISBN 10: 3659519715 / ISBN 13: 9783659519710

Published by LAP LAMBERT Academic Publishing, 2014

About this Item

nach der Bestellung gedruckt Neuware - Printed after ordering - This study is carried out to design controlled release multilayered matrix tablets of antihypertensive drug. The aim of this research work is to reduce the frequency of dosing, decreasing the required dose employed, providing uniform drug delivery, reduction of side effects and enhancement of patient compliance of antihypertensive drug. The purpose of study to formulate and evaluate multi-layer matrix tablets using hydrophilic polymer, namely xanthan gum and chitosan by the wet granulation. Captopril was choosen as a model drug because of its higher water solubility. From the results obtained, the hydrophilic polymer xanthan gum and chitosan used individually could not sufficiently produce controlled release so must be combined in various ratios for effective oral controlled release to be achieved of multilayer matrix tablet that complied with all parameters. This book is a good guide for students who want to learn about formulation technology of multilayer matrix tablets along with their various evaluation parameters. This book will also work as a reference material for researchers, those are planning or already doing their research in this direction.

Seller Inventory # 9783659519710

Bibliographic Details

• Title: Formulation And Evaluation Of Multilayer Matrix Tablet
• Publisher: LAP LAMBERT Academic Publishing
• Publication Date: 2014
• Language: English
• ISBN 10: 3659519715
• ISBN 13: 9783659519710
• Binding: Taschenbuch
• Condition: Neu
• Dimensions: 220W x 150H x 11D millimeters 220 millimeters width by 150 millimeters height by 11 millimeters depth
• Weight: 256 grams

About this title

Synopsis

This study is carried out to design controlled release multilayered matrix tablets of antihypertensive drug. The aim of this research work is to reduce the frequency of dosing, decreasing the required dose employed, providing uniform drug delivery, reduction of side effects and enhancement of patient compliance of antihypertensive drug. The purpose of study to formulate and evaluate multi-layer matrix tablets using hydrophilic polymer, namely xanthan gum and chitosan by the wet granulation. Captopril was choosen as a model drug because of its higher water solubility. From the results obtained, the hydrophilic polymer xanthan gum and chitosan used individually could not sufficiently produce controlled release so must be combined in various ratios for effective oral controlled release to be achieved of multilayer matrix tablet that complied with all parameters. This book is a good guide for students who want to learn about formulation technology of multilayer matrix tablets along with their various evaluation parameters. This book will also work as a reference material for researchers, those are planning or already doing their research in this direction.

About the Author

Ghanshyam Yadav has completed his B. Pharm and M. Pharm Meerut Institute of Engineering & Technology, Meerut. He has also qualified GPAT in 2011. He is presently working in QC department of a reputed pharmaceutical company. He has completed this book work under the guidance of Mr. Mayank Bansal and Mrs. Sumedha Bansal.