Fragment Based Drug Design : Tools, Practical Approaches, and Examples

Language: English

Published by Elsevier Science & Technology, Academic Press, 2011

0123812747 / 9780123812742

Series: Book 125 of 272 - ISSN

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Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH

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nach der Bestellung gedruckt Neuware - Printed after ordering - There are numerous excellent reviews on fragment-based drug discovery (FBDD), but there are to date no hand-holding guides or protocols with which one can embark on this orthogonal approach to complement traditional high throughput screening methodologies. This Methods in Enzymology volume offers the tools, practical approaches, and hit-to-lead examples on how to conduct FBDD screens. The chapters in this volume cover methods that have proven to be successful in generating leads from fragments, including chapters on how to apply computational techniques, nuclear magnetic resonance, surface plasma resonance, thermal shift and binding assays, protein crystallography, and medicinal chemistry in FBDD. Also elaborated by experienced researchers in FBDD are sample preparations of fragments, proteins, and GPCR as well as examples of how to generate leads from hits.

Seller Inventory # 9780123812742

Title
Fragment Based Drug Design : Tools, Practical Approaches, and Examples
Author
Lawrence C. Kuo
Publisher
Elsevier Science & Technology, Academic Press
Publication year
2011
Condition
Neu
Binding
Buch
Language
English
ISBN 10
0123812747
ISBN 13
9780123812742
Item weight
1,190 grams
Dimensions
229x152x33 mm
Series
Book 125 of 272: ISSN

AHA-BUCH GmbH

Einbeck, Germany

5-star seller

AbeBooks seller since August 14, 2006

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Item7 to 10 business days5 to 7 business days
First itemUS$ 49.36US$ 67.53
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