Gangliosides and Modulation of Neuronal Functions

Hinrich Rahmann

ISBN 10: 3642719341 / ISBN 13: 9783642719349

Published by Springer Berlin Heidelberg, 2011

About this Item

Druck auf Anfrage Neuware - Printed after ordering - The NATO Advanced Research Workshop on 'Gangliosides and Modu lation of Neuronal Functions' was held at the University of Stutt gart-Hohenheim, Federal Republic of Germany, on October 20 - 24, 1986. About 70 participants from 10 countries presented papers on a wide range of topics all concerning the ganglioside theme. The content of the workshop consisted of the following chap ters: (1) Fundamentals for research on function of gangliosides; (2) Brain ganglioside metabolism; (3) Cell specific distribution and differentiation-related ex pression of brain gangliosides; (4) Gangliosides and neuronal plasticity; (5) Bio-medical potential of exogenous ganglioside application on neuronal function; and (6) Critical assessments on aspects of ganglioside therapy. The aim of the workshop was to sum up and discuss the present knowledge in the respective fields. Despite intensive research on gangliosides ever since Ernst Klenk discovered them in 1936, the biological function of. these amphiphilic, 'sphinx-like' glycosphingo lipids remains elusive. Over the past few years, several thousands of articles on gangliosides have been published demonstrating very special properties of these glycolipids and their possible in volvement in diverse biological phenomena. As far as we know up to the present time, these properties may be due to particular physico-chemical attributes of these compounds, especially in com bination with calcium. The results obtained so far have shed light not only on pos sible functional roles of gangliosides with regard to cellular induction and organization, but have also unexpectedly opened up VI a whole new field of therapeutic applications for these compounds.

Seller Inventory # 9783642719349

Bibliographic Details

• Title: Gangliosides and Modulation of Neuronal Functions
• Publisher: Springer Berlin Heidelberg
• Publication Date: 2011
• Language: English
• ISBN 10: 3642719341
• ISBN 13: 9783642719349
• Binding: Taschenbuch
• Condition: Neu
• Dimensions: 244W x 170H x 36D millimeters 244 millimeters width by 170 millimeters height by 36 millimeters depth
• Weight: 1140 grams

About this title

Synopsis

The NATO Advanced Research Workshop on "Gangliosides and Modu­ lation of Neuronal Functions" was held at the University of Stutt­ gart-Hohenheim, Federal Republic of Germany, on October 20 - 24, 1986. About 70 participants from 10 countries presented papers on a wide range of topics all concerning the ganglioside theme. The content of the workshop consisted of the following chap­ ters: (1) Fundamentals for research on function of gangliosides; (2) Brain ganglioside metabolism; (3) Cell specific distribution and differentiation-related ex­ pression of brain gangliosides; (4) Gangliosides and neuronal plasticity; (5) Bio-medical potential of exogenous ganglioside application on neuronal function; and (6) Critical assessments on aspects of ganglioside therapy. The aim of the workshop was to sum up and discuss the present knowledge in the respective fields. Despite intensive research on gangliosides ever since Ernst Klenk discovered them in 1936, the biological function of. these amphiphilic, "sphinx-like" glycosphingo­ lipids remains elusive. Over the past few years, several thousands of articles on gangliosides have been published demonstrating very special properties of these glycolipids and their possible in­ volvement in diverse biological phenomena. As far as we know up to the present time, these properties may be due to particular physico-chemical attributes of these compounds, especially in com­ bination with calcium. The results obtained so far have shed light not only on pos­ sible functional roles of gangliosides with regard to cellular induction and organization, but have also unexpectedly opened up VI a whole new field of therapeutic applications for these compounds.