General and Applied Toxicology

Now in its Second Edition, and with contributions from over 160 of the world's leading experts in the field of toxicology, this lauded reference provides a comprehensive review of the scientific basis of toxicology and its many applications. The Second Edition contains over 20 new chapters providing additional coverage of applied and environmental toxicology, and all the chapters from the first edition have been thoroughly updated and completely revised. In addition, each of the work's three volumes includes a separate subject and chemical index for ready reference.This new edition has been significantly expanded and covers the following topics:
-- Basic scientific aspects of toxicology
-- Techniques and laboratory procedures
-- Information resources
-- Toxicity by routes
-- Target organs and tissues
-- Genetic toxicology
-- Carcinogenicity
-- Developmental and reproductive toxicology
-- Environmental toxicology
-- Specialist aspects (clinical, forensic, occupational, and veterinary)
-- Regulatory toxicology
-- Hazard evaluation and risk assessment
-- Biomarkers and biological monitoring
-- Educational, ethical, and legal considerations
-- Toxicology of special groups of substances

Bryan Ballantyne, MD, DSc, PhD, FFOM, FACOM, FAACT, FATS, FRCPath, FIBiol (deceased) was an IndependentConsultant in Occupational and Clinical Toxicology. Prior to that he held the positions of: Director of Applied Toxicology for Union Carbide Corporation in Connecticut, USA; Senior Medical Officer and Head of the Section of Toxicology and Pathology at the UK Chemical Defense Establishment; Adjunct Professor of Toxicology at the University of Pittsburgh; and Adjunct Professor of Pharmacology and Toxicology at West Virginia University. He was a Fellow of the Faculty of Occupational Medicine, Royal College of Pathologists, Academy of Toxicological Sciences, and the Institute of Biology. He was formerly a member of the Scientific Subcommittee on Pesticides of the Ministry of Agriculture, Fisheries and Food, UK and of the Committee of Experts on Pesticides, Council of Europe. He has been a member of the Council on Scientific Affairs of the American College of Occupational and Environmental Medicine, and of the Board of Trustees of the American Academy of Clinical Toxicology. Dr. Ballantyne was also the editor or co-editor of seven books on toxicology and related areas and a member of the Editorial Board of fi ve toxicology journals, including Toxicology Methods, Forensic Science International, and the Journal of Applied Toxicology.

Timothy Marrs, MD, DSc, MRCP, FRCPath, FIBiol is a consulting toxicologist for Edentox. He was formerly chief toxicologist at the Food Standards Agency in London, and before that Senior Medical Offi cer at the Department of Health. Previous to that, he was Senior Medical Offi cer (Research) at the Chemical Defence Establishment, Porton Down. He is also consulting clinical toxicologist at the West Midlands Poisons Unit in Birmingham. He is a Fellow of the Royal College of Pathologists, Royal College of Physicians of London and of the Academy of Toxicological Sciences. He has also been the editor of a number of books including, Organophosphates and Health and most recently Chemical Warfare Agents Toxicology and Treatment. He has written a number of papers on toxicology and allied subjects. He is a member of a number of government committees.

Tore Syversen, MSc, DrPhil is Professor of Pharmacology and Toxicology at the Norwegian University of Science and Technology Trondheim, Norway. He has been professor of toxicology at NTNU since 1977 and has been engaged in the teaching of toxicology to students of medicine, natural sciences and technology. His main research interest has been metals in health, nutrition as well as in occupational medicine and environmental sciences. Current interests also include using cell cultures for mechanism studies as well as the health challenges introduced by nanoparticles.