Generation and Effector Functions of Regulatory Lymphocytes

ISBN 10: 0470850744 / ISBN 13: 9780470850749

Published by Wiley & Sons, Incorporated, John, 2003

About this Item

Former library copy. Pages intact with possible writing/highlighting. Binding strong with minor wear. Dust jackets/supplements may not be included. Includes library markings. Stock photo provided. Product includes identifying sticker. Better World Books: Buy Books. Do Good.

Seller Inventory # 58203108-75

Bibliographic Details

• Title: Generation and Effector Functions of Regulatory Lymphocytes
• Publisher: Wiley & Sons, Incorporated, John
• Publication Date: 2003
• Language: English
• ISBN 10: 0470850744
• ISBN 13: 9780470850749
• Binding: Hardcover
• Condition: Very Good
• Weight: 1.446 pounds

About this title

Synopsis

Over the last several years, immunologists have re-discovered the importance of regulatory lymphocytes, formerly termed 'suppressor cells'. Many recent reports have documented their existence, effector functions and potential therapeutic benefits in autoimmunity and transplantation. However, even though modern techniques have allowed us to get a much more detailed picture of these cells, they are still highly controversial. Several unresolved issues responsible for this dilemma are discussed in this book: it is difficult to grow and clone such cells, their phenotypes and effector functions are diverse and can sometimes easily be lost, and it is not well understood how they interact with antigen-presenting cells.

This book contains contributions from leading investigators from around the world, including lively discussion of the current state of the art in studies of regulatory lymphocytes. Topics featured are the physiological control of autoimmunity, the role of antigen-specific cells in various diseases and disease models and effector mechanisms. Therapeutic applications are considered, particularly for type 1 diabetes, tissue transplantation and the control of viral infection. This important and groundbreaking book should be of interest to all immunologists.

Related Novartis Foundation symposia:

254 Immunoinformatics: bioinformatic strategies for better understanding of immune function
Chair: Hans-Georg Rammensee

256 Cancer and inflammation
Chair: Siamon Gordon

About the Author

The Novartis Foundation is an international scientific and educational charity which promotes the study and general knowledge of science and in particular encourages international co-operation in scientific research.