Genes and Cancer

Language: English

Published by Intechopen, 2019

1789844266 / 9781789844269

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Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH

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nach der Bestellung gedruckt Neuware - Printed after ordering - Cancer is a malignant tumor caused by DNA damage, which leads to uncontrolled cell growth. Tumor progression is locally favored by the mitogenic effects of hormones or growth factors, which stimulate the tumor's growth, or the activation of vascular endothelial growth factor receptor, which induces angiogenesis and leads to metastasis. About 300 out of 25,000 genes that set up the human genome are involved in cancer pathology. These genes are divided into three groups: oncogenes, tumor suppressor genes, and DNA repair genes. Activated oncogenes promote the development of cancer, whereas the tumor suppressor and DNA repair genes have a protective role by respectively inhibiting cell cycle progression and inducing apoptosis, or by repairing DNA damage occurring during the cell cycle. This book discusses the issue of tumor suppressor genes through chapters written by experts using advanced biochemistry, cell, and molecular biology tools. The tumor suppressor genes can be used as markers of risk to identify populations with high risk or targets for cancer treatment and therapeutic resistance. We hope that the work provided in this book will be useful for researchers and students and will increase knowledge of the understanding of cancer and improve its treatment.

Seller Inventory # 9781789844269

Title
Genes and Cancer
Author
Guy-Joseph Lemamy
Publisher
Intechopen
Publication year
2019
Condition
Neu
Binding
Buch
Language
English
ISBN 10
1789844266
ISBN 13
9781789844269
Item weight
494 grams
Dimensions
266x185x14 mm

AHA-BUCH GmbH

Einbeck, Germany

5-star seller

AbeBooks seller since August 14, 2006

Shipping rates from Germany to U.S.A.

Item30 to 40 business days7 to 14 business days
First itemUS$ 72.35US$ 83.93
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