Genetic Disorders of Human Sexual Development: 38 (Oxford Monographs on Medical Genetics)

Pinsky, Leonard

ISBN 10: 0195109074 / ISBN 13: 9780195109078

Published by OUP USA, 1999

About this Item

Authoritative clinical reference on genetic sexual disorders, a field that has been transformed in many areas by molecular genetics. Series: Oxford Monographs on Medical Genetics. Num Pages: 432 pages, 6 halftones, line drawings. BIC Classification: MFN; MJC; MJS. Category: (P) Professional & Vocational. Dimension: 264 x 186 x 29. Weight in Grams: 1234. . 1999. Illustrated. hardcover. . . . . Books ship from the US and Ireland.

Seller Inventory # V9780195109078

Bibliographic Details

• Title: Genetic Disorders of Human Sexual Development: 38 (Oxford Monographs on Medical Genetics)
• Publisher: OUP USA
• Publication Date: 1999
• Language: English
• ISBN 10: 0195109074
• ISBN 13: 9780195109078
• Binding: Hardcover
• Condition: New

About this title

Synopsis

There have been many exciting advances in our understanding of mammalian sex determination and differentiation in the last decade. Using these advances to elucidate clinical conditions of abnormal sexual development, the authors bring together great expertise in molecular endocrinology, molecular genetics, and dysmorphology. The text begins with a discussion of normal gonadal and sexual development that presents enough embryology, biochemistry, and endocrinology to make the remaining chapters easy to assimilate. Then the authors discuss overarching clinical issues that are common to genetic abnormalities of gonadal and sexual development, providing a detailed account of genetic causes of gonadal maldevelopment, followed by a compendium of the singular, syndromal, endocrinologic, and systemic-metabolic genetic causes of sexual maldevelopment. The final section describes genetic forms of gamete failure.
Seldom dogmatic, this unconventional textbook frequently presents alternatives, highlights speculation, raises questions, and attempts to provide answers. Yet it will be a uniquely valuable reference on an area of genetic medicine where much has happened in recent years. This book will be welcomed by medical geneticists, genetic counselors, endocrinologists, gynecologists, urologists, and students who need fully-referenced information about the genetic aspects of humans sexual maldevelopment in order to better manage their patients and their patients families.

About the Author

Leonard Pinsky, M.D., is Chairman of the Department of Human Genetics and Professor in the Departments of Human Genetics, Medicine, and Pediatrics at McGill University. He also serves as Director of the Division of Genetics at Sir Mortimer B. Davis-Jewish General Hospital and Co-Director of the Androgen Receptor Laboratory at the Lady Davis Institute for Medical Research in Montreal.