Genome Analysis: Principles and Methods

Genome Analysis: Principles and Methods provides recent and advanced information about genome analysis approaches and techniques to study and annotate the structure and function of the genome. It is a compendium of important topics such as NGS analysis, genome fragmentation and assembly, metagenomics, cloning and expression, physical marker analysis, transcriptome data analysis, sequence alignment and comparison, evolutionary analysis, SNP analysis, genome-based disease diagnosis and therapies, micro-RNAs, pharmacogenomics, genetic approaches to disease intervention, and challenges with opportunities in genome analysis and genomics, etc.

The latest developments in the field are discussed, and key concepts are introduced to ensure readers understand advanced concepts and methodologies in the area. The book serves as a valuable guide to the present, emerging, and evolving research methodologies in the field.

• Contains chapters written by leading global experts actively engaged in their respective research topic
• Provides a wide-ranging collection of 24 chapters related to the field of genomics and genome analysis
• Presents a broad picture of current, emerging, and evolving advances and applications of genomics

Dr. Dev Bukhsh Singh is Assistant Professor in the Department of Biotechnology at Siddharth University, Kapilvastu, India, a position he has held since 2021. Previously, he served as Assistant Professor in the Department of Biotechnology at Chhatrapati Shahu Ji Maharaj University, Kanpur, India, from 2009 to 2021. His research focuses on medicinal biology, lead compound discovery, and drug design. He has been involved in teaching and mentoring undergraduate and postgraduate students in biotechnology since 2009. Dr. Singh has edited books in the areas of protein structure and function, computer-aided drug design, Protein-based therapeutics, medicinal biotechnology, genomics, and bioinformatics. He is a member of professional academic organizations and serves as a reviewer for scholarly journals. His academic interests include applying computational and biotechnological approaches to drug discovery and related life science research.

Dr. Timir Tripathi is a Professor of Molecular Biology, School of Life Sciences, North-Eastern Hill University, Shillong, India. He previously held positions as Regional Director of IGNOU in Kohima and a Senior Assistant Professor in the Department of Biochemistry at NEHU. His research focuses on protein–substrate interactions, conformational dynamics, and the regulatory roles of non-catalytic domains. He is especially interested in intrinsically disordered and phase-separated proteins, their roles in disease, and, more recently, molecular memory, adaptive learning, and intelligence in proteins. Professor Tripathi has received several awards and is an Associate Fellow of the Indian National Science Academy, New Delhi, and an elected member of the National Academy of Sciences, India. He is a section editor of Elsevier's International Journal of Biological Macromolecules and has published five books with Elsevier.