Genomics : The Science and Technology Behind the Human Genome Project

Charles R Cantor

ISBN 10: 0471599085 / ISBN 13: 9780471599081

Published by Wiley Mär 1999, 1999

About this Item

Neuware - Wissenschaftler aus aller Welt sind am Human Genome Project beteiligt, einem Projekt zur Erfassung aller Erbinformationen, die auf den 23 Chromosomenpaaren des Menschen gespeichert sind. Dies könnte zu enormen Fortschritten in der Behandlung von Erbkrankheiten führen. Erklärt werden die Grundprinzipien der im Projekt und in der modernen Molekulargenetik verwendeten Strategien und Technologien. Ebenso werden die chemischen und biologischen Eigenschaften von DNA und Chromosomen besprochen sowie die drei wichtigsten Verfahren der DNA-Analyse.

Seller Inventory # 9780471599081

Bibliographic Details

• Title: Genomics : The Science and Technology Behind the Human Genome Project
• Publisher: Wiley Mär 1999
• Publication Date: 1999
• Language: English
• ISBN 10: 0471599085
• ISBN 13: 9780471599081
• Binding: Buch
• Condition: Neu
• Dimensions: 259W x 184H x 33D millimeters 259 millimeters width by 184 millimeters height by 33 millimeters depth
• Weight: 1252 grams

About this title

Synopsis

A unique exploration of the principles and methods underlying the Human Genome Project and modern molecular genetics and biotechnology-from two top researchers
In Genomics, Charles R. Cantor, former director of the Human Genome Project, and Cassandra L. Smith give the first integral overview of the strategies and technologies behind the Human Genome Project and the field of molecular genetics and biotechnology. Written with a range of readers in mind-from chemists and biologists to computer scientists and engineers-the book begins with a review of the basic properties of DNA and the chromosomes that package it in cells. The authors describe the three main techniques used in DNA analysis-hybridization, polymerase chain reaction, and electrophoresis-and present a complete exploration of DNA mapping in its many different forms. By explaining both the theoretical principles and practical foundations of modern molecular genetics to a wide audience, the book brings the scientific community closer to the ultimate goal of understanding the biological function of DNA. Genomics features:
* Topical organization within chapters for easy reference
* A discussion of the developing methods of sequencing, such as sequencing by hybridization (SBH) in which data is read through words instead of letters
* Detailed explanations and critical evaluations of the many different types of DNA maps that can be generated-including cytogenic and restriction maps as well as interspecies cell hybrids
* Informed predictions for the future of DNA sequencing

About the Author

CHARLES R. CANTOR, formerly principal scientist of the DOE Human Genome Project, is the Chief Scientific Officer of Sequenom, Inc., in San Diego. Dr. Cantor is on leave from Boston University, where he is Professor of Biomedical Engineering and Director of the Center for Advanced Biotechnology.
CASSANDRA L. SMITH is Deputy Director of the Center for Advanced Biotechnology and Professor of Biomedical Engineering, Biology, and Pharmacology at Boston University.