Glycoscience and Microbial Adhesion

Thisbe K. Lindhorst

ISBN 10: 3642425445 / ISBN 13: 9783642425448

Published by Springer Vieweg, 2014

About this Item

Druck auf Anfrage Neuware - Printed after ordering - bacterial carbohydrate recognition are conveyed, covering Gram-positive as well as Gram-negative bacteria, in Chapter 4 Streptococci and Staphylococci, and in Chapter 5, carbohydrate binding specificities of Helicobacter pylori. In Chapter 6, Bitter sweetness of complexity, the collected reflections on mic- bial adhesion are expanded by a perspective on a broader impact of glycosylation on cellular adhesion, motility and regulatory processes, paralleling the complexity of N-glycan structures on cell surfaces. It highlights particularly how structural details of N-glycans have been causally related to pathological scenarios, with a focus on (1,6)-N-acetylglucosaminyltransferase. In the final chapter, biofilm formation is reviewed, covering knowledge about structure and biosynthesis of polysaccharide intercellular adhesins (PIAs) which are central to biofilm formation. This comprehensive chapter explains all PIA-related principles of medical device-associated infections. It is our hope, that this collection of expert articles, ranging from structural ch- istry and structural biology to biochemistry and medicine, will be a stimulation and motivation for our colleagues in the life sciences. At the same time, we hope that these reflections on microbial adhesion will awake interest in and promote und- standing of the complex processes associated with the glycocalyx and the multif- eted interactions between the host cell and its guest, as well as the biological consequences resulting from this mutual interplay.

Seller Inventory # 9783642425448

Bibliographic Details

• Title: Glycoscience and Microbial Adhesion
• Publisher: Springer Vieweg
• Publication Date: 2014
• Language: English
• ISBN 10: 3642425445
• ISBN 13: 9783642425448
• Binding: Taschenbuch
• Condition: Neu
• Dimensions: 235W x 155H x 12D millimeters 235 millimeters width by 155 millimeters height by 12 millimeters depth
• Weight: 312 grams

About this title

Synopsis

Bitter Sweetness of Complexity.- Carbohydrate Receptors of Bacterial Adhesins: Implications and Reflections.- Structure, Function, and Assembly of Type 1 Fimbriae.- The Multiple Carbohydrate Binding Specificities of Helicobacter pylori.- Ins and Outs of Microbial Adhesion.- Staphylococcus epidermidis Biofilms: Functional Molecules, Relation to Virulence, and Vaccine Potential.- Architectures of Multivalent Glycomimetics for Probing Carbohydrate-Lectin Interactions.