Glycoscience and Microbial Adhesion (Topics in Current Chemistry, Volume 288)

Lindhorst, Thisbe K.; Oscarson, Stefan

ISBN 10: 3642013031 / ISBN 13: 9783642013034

Published by Springer, Germany, 2009

About this Item

9783540690368. Unread hardcover, from closed pharmaceutical company library. English text. 197 pages, Subject Index, illustrated with charts, tables and diagrams. Sections: Ins and Outs of Microbial Adhesion; Architectures of Multivalent Glycomimetics for Probing Carbohydrate-Lectin Interactions; Structure, Function, and Assembly of Type 1 Fimbriae; Carbohydrate Receptors of Bacterial Adhesins: Implications and Reflections; The Multiple Carbohydrate Binding Specificities of Helicobacter pylori; Bitter Sweetness of Complexity; Staphylococcus epidermidis Biofilms: Functional Molecules, Relation to Virulence, and Vaccine Potential. Contents unread, looks like new, clean, tight and bright.

Seller Inventory # 030378

Bibliographic Details

• Title: Glycoscience and Microbial Adhesion (Topics in Current Chemistry, Volume 288)
• Publisher: Springer, Germany
• Publication Date: 2009
• Language: English
• ISBN 10: 3642013031
• ISBN 13: 9783642013034
• Binding: Hardcover
• Condition: Near Fine
• Dust Jacket Condition: No Jacket
• Book Type: Book
• Seller catalogs:
  • Chemistry

About this title

Synopsis

bacterial carbohydrate recognition are conveyed, covering Gram-positive as well as Gram-negative bacteria, in Chapter 4 Streptococci and Staphylococci, and in Chapter 5, carbohydrate binding specificities of Helicobacter pylori. In Chapter 6, "Bitter sweetness of complexity," the collected reflections on mic- bial adhesion are expanded by a perspective on a broader impact of glycosylation on cellular adhesion, motility and regulatory processes, paralleling the complexity of N-glycan structures on cell surfaces. It highlights particularly how structural details of N-glycans have been causally related to pathological scenarios, with a focus on (1,6)-N-acetylglucosaminyltransferase. In the final chapter, biofilm formation is reviewed, covering knowledge about structure and biosynthesis of polysaccharide intercellular adhesins (PIAs) which are central to biofilm formation. This comprehensive chapter explains all PIA-related principles of medical device-associated infections. It is our hope, that this collection of expert articles, ranging from structural ch- istry and structural biology to biochemistry and medicine, will be a stimulation and motivation for our colleagues in the life sciences. At the same time, we hope that these reflections on microbial adhesion will awake interest in and promote und- standing of the complex processes associated with the glycocalyx and the multif- eted interactions between the host cell and its "guest," as well as the biological consequences resulting from this mutual interplay.