The Great Healthcare Disruption: Big Tech, Bold Policy, and the Future of American Medicine

Discover the innovations transforming medicine—and the fight to make care more equitable, accessible, and effective.

In The Great Healthcare Disruption, Dr. Marschall Runge—cardiologist, researcher, and CEO of Michigan Medicine—offers a gripping, insider’s look at the forces rapidly reshaping American healthcare. From artificial intelligence and retail medicine to revolutionary gene therapies and next-generation obesity drugs, this is your essential guide to the most significant transformation in medical care since the discovery of antibiotics.

Inside you’ll explore:

• The rise of Big Tech in medicine—how Amazon, Google, and other disruptors are redefining the patient experience
• Breakthrough treatments and AI-driven diagnostics reshaping chronic disease management, behavioral health, and drug development
• The hidden trade-offs of innovation—how cutting-edge care delivery models are improving outcomes while straining the systems meant to support them
• Why traditional institutions must evolve—and how academic medical centers can remain vital in a tech-driven world
• Hard truths about access, equity, and affordability—and what must change to make healthcare work for everyone

With rich storytelling, sharp insights, and practical solutions, Dr. Runge cuts through the complexity of modern medicine to offer a bold, balanced path forward.

Whether you're a healthcare professional, policy leader, or curious reader, The Great Healthcare Disruption is your guide to understanding—and shaping—the revolution already underway.

USA Today Bestseller
2025 Global Book Awards Gold Medalist in Organizational Change

MARSCHALL S. RUNGE, M.D., Ph.D., is the former executive vice president for Medical Affairs at the University of Michigan, dean of the Medical School, and CEO of Michigan Medicine. During his tenure in these leadership roles, Dr. Runge implemented transformative change and positioned Michigan Medicine and the Medical School internationally for continued success.