Greene's Protective Groups in Organic Synthesis, 2 Volume Set

Peter G. M. Wuts

ISBN 10: 1394233167 / ISBN 13: 9781394233168

Published by Wiley John + Sons Mai 2025, 2025

About this Item

Neuware -Integral, reliable, and comprehensive guidance for chemists performing the complex syntheses required for the formation and cleavage of protective groups Organic synthesis is the preparation and creation of organic compounds for use in natural products, pharmaceuticals, and other molecules. The synthesis of molecules having multiple functional groups often requires the use of 'protective groups' to achieve site selectivity in a chemical reaction within a molecule bearing multiple sites of reactivity. Protective groups are installed temporarily to prevent unwanted reactions at a particular site, while transforming a different functional group. Once they have served their function, they are removed to expose the original group. Without a thorough understanding of the methods required to install and remove them, the design of a synthesis of a molecule having multiple functional groups in most cases is effectively impossible. Greene's Protective Groups in Organic Synthesis, 6th Edition is the definitive compilation of protective groups, their classification, and their application in a wide array of situations. With a long tradition of comprehensive coverage, organized on the basis of the functional group in need of protection and subsequent deprotection, it is an essential reference and resource for all chemists involved in organic syntheses. Now fully updated to reflect the current state of the art, it remains an indispensable resource for generating life-changing organic products. This edition contains a new chapter on how protective groups effect reactivity and selectivity in carbohydrate chemistry. Readers of the sixth edition of Greene's Protective Groups in Organic Synthesis will also find: - Methodology for planning selectivity in organic syntheses - Detailed discussion of all major functional groups including ethers, amides, and phenols - A discussion of the impact of protective groups on reactivity in carbohydrates Greene's Protective Groups in Organic Synthesis is ideal for synthetic organic chemists or medicinal chemists in academia, industry - pharmaceuticals, food, agrochemicals, and biotech - or government agencies.

Seller Inventory # 9781394233168

Bibliographic Details

• Title: Greene's Protective Groups in Organic Synthesis, 2 Volume Set
• Publisher: Wiley John + Sons Mai 2025
• Publication Date: 2025
• Language: English
• ISBN 10: 1394233167
• ISBN 13: 9781394233168
• Binding: Buch
• Condition: Neu
• Dimensions: 263W x 209H x 76D millimeters 263 millimeters width by 209 millimeters height by 76 millimeters depth
• Weight: 3550 grams

About this title

Synopsis

Integral, reliable, and comprehensive guidance for chemists performing the complex syntheses required for the formation and cleavage of protective groups

Organic synthesis is the preparation and creation of organic compounds for use in natural products, pharmaceuticals, and other molecules. The synthesis of molecules having multiple functional groups often requires the use of ‘protective groups’ to achieve site selectivity in a chemical reaction within a molecule bearing multiple sites of reactivity. Protective groups are installed temporarily to prevent unwanted reactions at a particular site, while transforming a different functional group. Once they have served their function, they are removed to expose the original group. Without a thorough understanding of the methods required to install and remove them, the design of a synthesis of a molecule having multiple functional groups in most cases is effectively impossible.

Greene’s Protective Groups in Organic Synthesis, 6th Edition is the definitive compilation of protective groups, their classification, and their application in a wide array of situations. With a long tradition of comprehensive coverage, organized on the basis of the functional group in need of protection and subsequent deprotection, it is an essential reference and resource for all chemists involved in organic syntheses. Now fully updated to reflect the current state of the art, it remains an indispensable resource for generating life-changing organic products. This edition contains a new chapter on how protective groups effect reactivity and selectivity in carbohydrate chemistry.

Readers of the sixth edition of Greene’s Protective Groups in Organic Synthesis will also find:

• Methodology for planning selectivity in organic syntheses
• Detailed discussion of all major functional groups including ethers, amides, and phenols
• A discussion of the impact of protective groups on reactivity in carbohydrates

Greene’s Protective Groups in Organic Synthesis is ideal for synthetic organic chemists or medicinal chemists in academia, industry ― pharmaceuticals, food, agrochemicals, and biotech ― or government agencies.

About the Author

Peter G. M. Wuts, PhD, is a renowned organic chemist, currently working as a chemistry consultant for both the biotech and the legal community. He continues a 50-year career in academia and the pharmaceutical industry.