Guide to Mouse Development: 476 (Methods in Enzymology): Mice, Embryos, and Cells

Philippe Soriano

ISBN 10: 0123747759 / ISBN 13: 9780123747754

Published by Academic Press 2010-12-09, 2010

About this Item

Seller Inventory # 6666-ELS-9780123747754

Bibliographic Details

• Title: Guide to Mouse Development: 476 (Methods in Enzymology): Mice, Embryos, and Cells
• Publisher: Academic Press 2010-12-09
• Publication Date: 2010
• Language: English
• ISBN 10: 0123747759
• ISBN 13: 9780123747754
• Binding: Hardcover
• Condition: New

About this title

Synopsis

Guide to Techniques in Mouse Development, Part A comprehensively covers new technologies and methodologies that have appeared for the study of mouse development.

• Update of volume 225 of Methods in Enzymology, Guide to Techniques in Mouse Development, edited by P.M. Wassarman and M.L. DePamphilis and published in 1993
• Covers new technologies and methodologies, including:
• new techniques for the cryopreservation of gametes and embryos
• production of transgenic and null (knockout) animals (use of ES cells)
• generation of conditional/inducible mutant animals
• use of gene-trap mutagenesis
• analysis of allele-specific expresion
• use of new reporter constructs
• humanizing of transgenic animals
• transcript profiling of mouse development
• imaging of mouse development
• rederivation of animals and use of mouse genomics

About the Author

Philippe Soriano,is Professor of Cell, Developmental & Regenerative Biology and Professor of Oncological Sciences, Icahn School of Medicine at Mount Sinai, NY, USA