Guide to Techniques in Mouse Development, Part A: Mice, Embryos, and Cells (Methods in Enzymology)

ISBN 10: 0123848830 / ISBN 13: 9780123848833

Published by Academic Press, 2010

About this Item

Seller Inventory # SHUB57335

Bibliographic Details

• Title: Guide to Techniques in Mouse Development, Part A: Mice, Embryos, and Cells (Methods in Enzymology)
• Publisher: Academic Press
• Publication Date: 2010
• Language: English
• ISBN 10: 0123848830
• ISBN 13: 9780123848833
• Binding: Soft cover
• Condition: New

About this title

Synopsis

This volume comprehensively covers new technologies and methodologies that have appeared for the study of mouse development.

• First of a 2 part update of volume 225, Guide to Techniques in Mouse Development, edited by P.M. Wassarman and M.L. DePamphilis and published in 1993
• Comprehensively covers:
• new techniques for the cryopreservation of gametes and embryos
• production of transgenic and null (knockout) animals (use of ES cells)
• generation of conditional/inducible mutant animals
• use of gene-trap mutagenesis
• analysis of allele-specific expression
• use of new reporter constructs
• humanizing of transgenic animals
• transcript profiling of mouse development, imaging of mouse development
• rederivation of animals and use of mouse genomics

About the Author

Philippe Soriano,is Professor of Cell, Developmental & Regenerative Biology and Professor of Oncological Sciences, Icahn School of Medicine at Mount Sinai, NY, USA