Guide to Techniques in Mouse Development, Part B: Mouse Molecular Genetics: 477 (Methods in Enzymology)

Paul Wassarman, Philippe M Soriano Dr.

ISBN 10: 0123848806 / ISBN 13: 9780123848802

Published by Academic Press 2010-09-24, 2010

About this Item

Seller Inventory # 6666-ELS-9780123848802

Bibliographic Details

• Title: Guide to Techniques in Mouse Development, Part B: Mouse Molecular Genetics: 477 (Methods in Enzymology)
• Publisher: Academic Press 2010-09-24
• Publication Date: 2010
• Language: English
• ISBN 10: 0123848806
• ISBN 13: 9780123848802
• Binding: Hardcover
• Condition: New

About this title

Synopsis

This volume comprehensively covers new technologies and methodologies that have appeared for the study of mouse development

• Update of volume 225, Guide to Techniques in Mouse Development, edited by P.M. Wassarman and M.L. DePamphilis and published in 1993
• Comprehensively covers:
• new techniques for the cryopreservation of gametes and embryos
• production of transgenic and null (knockout) animals (use of ES cells)
• generation of conditional/inducible mutant animals, use of gene-trap mutagenesis
• analysis of allele-specific expression, use of new reporter constructs
• humanizing of transgenic animals
• transcript profiling of mouse development
• imaging of mouse development
• rederivation of animals and use of mouse genomics

About the Author

Philippe Soriano,is Professor of Cell, Developmental & Regenerative Biology and Professor of Oncological Sciences, Icahn School of Medicine at Mount Sinai, NY, USA