Guide to Techniques in Mouse Development, Part A comprehensively covers new technologies and methodologies that have appeared for the study of mouse development.

Update of volume 225 of Methods in Enzymology, Guide to Techniques in Mouse Development, edited by P.M. Wassarman and M.L. DePamphilis and published in 1993
Covers new technologies and methodologies, including:

new techniques for the cryopreservation of gametes and embryos
production of transgenic and null (knockout) animals (use of ES cells)
generation of conditional/inducible mutant animals
use of gene-trap mutagenesis
analysis of allele-specific expresion
use of new reporter constructs
humanizing of transgenic animals
transcript profiling of mouse development
imaging of mouse development
rederivation of animals and use of mouse genomics

About the Author

Philippe Soriano,is Professor of Cell, Developmental & Regenerative Biology and Professor of Oncological Sciences, Icahn School of Medicine at Mount Sinai, NY, USA

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