Guidelines and Screening Methods of Pharmacology

Contents: 1. Regulations for laboratory animals care and ethical requirements. 2. Pharmacological techniques for evaluation of drugs on different systems. 3. Bioassay. 4. Evaluation of drugs acting on autonomic nervous system. 5. Evaluation of drugs acting on central nervous system. 6. Evaluation of drugs acting on respiratory system. 7. Evaluation of drugs acting on eye. 8. Evaluation of drugs acting on cardiovascular system. 9. Evaluation of drugs acting on endocrine system. 10. Evaluation of drug acting on kidney. 11. Miscellaneous. 12. Transgenic animals and other genetically modified animal models. 13. Drug toxicity and safety evaluation. 14. Alternatives to animal screening procedures. 15. New approaches in drug discovery. 16. Research methodology. Drug Discovery is the process by which new molecules are discovered and now a days everybody is becoming aware of its level of importance especially in this era of COVID 19, which creates a possible anticipation of an increment in the demand for books related to screening methods of pharmacology. Pharmacological screening of drugs is a sequential testing of new chemical entities or extracts from biological material in isolated organs followed by test in whole experimental animals. Screening Methods in Pharmacology focuses on the methods for screening of moieties for pharmacological activities and discussions for organization of screening programs. This book envelops a descriptive approach detailed about CPCSEA, OECD and ICH guidelines that must be followed during screening of new drug moieties. It also provides a brief idea about bioassay and research methodology along with various experimental animal screening models for different diseases. This book shall serve as a reference guide for students of Pharmacy and life sciences graduates.…