HIV and the Brain: New Challenges in the Modern Era (Current Clinical Neurology)

Tashima Karen Tokie Valcour Victor Sacktor Ned Charlton Paul Robert H.

ISBN 10: 1934115088 / ISBN 13: 9781934115084

Published by Humana Press, 2009

About this Item

pp. x + 350.

Seller Inventory # 18481994

Bibliographic Details

• Title: HIV and the Brain: New Challenges in the Modern Era (Current Clinical Neurology)
• Publisher: Humana Press
• Publication Date: 2009
• Language: English
• ISBN 10: 1934115088
• ISBN 13: 9781934115084
• Binding: Hardcover
• Condition: New

About this title

Synopsis

It is now more than a quarter century since the appearance of the f irst reported cases of the acquired immunodeficiency syndrome (AIDS). Although successful tre- ments with highly active antiretroviral therapies have made a major impact on survival, there still remains no vaccine for prevention and the available therapies do not cure the disease. As a result, AIDS has been transformed into a chronic, lifelong disease which requires continuous antiretro viral drug treatment together with ongoing treatment of the associated systemic medical complications. It appears that as survival improves, the prevalence of chronic central nervous system involvement may be increasing. As pointed out by the editors of this volume, this shift in emphasis requires further examination of how AIDS affects the brain in terms of cogniti ve function, neuropsychiatric manifestations, activities of daily living, and quality of life. They also go on to ask the interesting question of how AIDS involvement of the brain interacts with normal aging. In HIV and the Brain, Drs. Paul, Sacktor, Valcour, and Tashima have assembled an impressive international team of experts to summarize the current state of kno- edge concerning brain function in AIDS. Early chapters re view epidemiology, pathophysiology, neuropathology, neuroimaging, and HIV genetics follo wed by a series of chapters concerning the neuropsychological, behavioral, and neuropsyc- atric aspects of the disease.

From the Back Cover

Within the last decade there have been a number of new and important areas of emphasis in HIV care and research, particularly in the context of brain involvement. Without question, clinical and research innovations in the modern era of the HIV pandemic warrant an update on HIV and the brain. Written by a panel of leading experts, HIV and the Brain: New Challenges in the Modern Era offers a clear picture of brain impairment associated with the virus with particular focus on three emerging areas including different genetic strains of the virus throughout the world, interactions between advanced age and HIV, and the impact of HIV on the brain in the context of chronic, long-term treatment with highly active antiretroviral therapy (HAART). HIV and the Brain: New Challenges in the Modern Era provides a comprehensive review of both basic science and clinical implications in these important areas of the disease. The text is of particular relevance to both research scientists and clinicians involved in HIV in the modern era.