Handbook on Analyzing Human Genetic Data

Hongyu Zhao

ISBN 10: 3642424813 / ISBN 13: 9783642424816

Published by Springer Berlin Heidelberg, Springer Berlin Heidelberg Nov 2014, 2014

About this Item

Neuware -The discipline of statistical genetics is highly computational. Be it exact compu- tionalmethods,simulationbased,orahybridofthetwo,computationalpackagesare indispensable tools and constant companions of researchers in the eld. This ha- bookisintendedtoprovidehumangeneticistsandotherbiomedicalresearcherswith guidance on selections of appropriate computational methods and software pa- ages for their speci c genetic problems. It may also be used by students and other learners as a reference in conjunction with a more theoretical and/or methodolo- cally oriented text book. This book tries to strike a balance between methodological expositions and practical guidelines for software selections. Wherever possible, comparisons among the competing methods and software are made to highlight the relativeadvantagesanddisadvantagesoftheapproaches,so thatthe readercanmake informed choices to best match their speci c needs. Human genetics has been undergoing an evolution in the past several years as new knowledge and technologies are transforming the eld, leading to numerous new discoveriesof genes associated with complex traits such as cancer, obesity, and diabetes. Many recent genome-wide association studies employ the case¿control design, where the study subjects consist of unrelated affected individuals and n- mal controls. For each individual, a large number of genetic markers are queried.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 348 pp. Englisch.

Seller Inventory # 9783642424816

Bibliographic Details

• Title: Handbook on Analyzing Human Genetic Data
• Publisher: Springer Berlin Heidelberg, Springer Berlin Heidelberg Nov 2014
• Publication Date: 2014
• Language: English
• ISBN 10: 3642424813
• ISBN 13: 9783642424816
• Binding: Taschenbuch
• Condition: Neu

About this title

Synopsis

This handbook provides human geneticists and other biomedical researchers with guidance on selections of appropriate computational methods and software packages for their specific genetic problems. It may also be used by students and other learners as a reference in conjunction with a more theoretical and/or methodologically oriented text book. Coverage strikes a balance between methodological expositions and practical guidelines for software selections. Wherever possible, comparisons among competing methods and software are made to highlight the relative advantages and disadvantage of the approaches so that readers can make informed choices to best match their specific needs.

From the Back Cover

The discipline of statistical genetics is highly computational. Be it exact computational methods, simulation based, or a hybrid of the two, computational packages are indispensable tools and constant companions of researchers in the field. This handbook is intended to provide human geneticists and other biomedical researchers with guidance on selections of appropriate computational methods and software packages for their specific genetic problems. It may also be used by students and other learners as a reference in conjunction with a more theoretical and/or methodologically oriented text book. This book tries to strike a balance between methodological expositions and practical guidelines for software selections. Wherever possible, comparisons among competing methods and software are made to highlight the relative advantages and disadvantage of the approaches so that the readers can make informed choices to best match their specific needs.