The classic textbook of principles and techniques for practitioners, researchers, and undergraduate and graduate students involved in various applications of pharmacokinetics. Spanning 38 detailed chapters and an appendix providing pharmacokinetic data profiles on more than 420 drugs, this book includes information that is both current and accurate. Presented in a manner that fosters clinical application, readers will gain an understanding of the more precise equations for determining pharmacokinetic values.

From the Back Cover

The sixth edition of the classic pharmacokinetics handbook remains a user-friendly consolidation of principles and techniques for practitioners, researchers, and students involved in the various applications of pharmacokinetics. Readers will find the book current, accurate, comprehensive, and useful clinically.

“This book will be useful to clinicians, educators, and students. It presents a wealth of material clearly, concisely, and efficiently.”
-From review of 5th edition by Thomas M. Guenthner, PhD Doody’s Health Sciences Book Review Journal

Highlights:
*13 of previous edition’s 38 chapters have been updated to capture the most relevant new scientific information
*New chapter entitled “Pharmacogenetics and Pharmacogenomics” was created in recognition of the influence of genetic constitution on the enzymes and transporters that affect drug disposition and action
*Appendix presents pharmacokinetic data on more than 640 important drugs—more than 220 new to this edition—in an accessible tabular format
*A wealth of useful figures (numbering 130) and tables (90)
*Glossary and index

About the Authors: Wolfgang A. Ritschel is one of the discipline’s most prominent experts worldwide. He is author or coauthor of more than 450 papers and of 13 books in pharmacokinetics, biopharmaceutics, technology, and pharmacology. He is Professor Emeritus of Pharmacokinetics and Biopharmaceutics at the University of Cincinnati College of Pharmacy and Professor of Pharmacology and Cell Biophysics at the University of Cincinnati College of Medicine.

Gregory L. Kearns is Marion Merrell Dow/Missouri Chair in Pediatric Pharmacology and Professor of Pediatrics and Pharmacology at the University of Missouri–Kansas City. He is also Chief, Division of Pediatric Pharmacology and Medical Toxicology and Director, Pediatric Pharmacology Research Unit, at Children’s Mercy Hospitals and Clinics in Kansas City, Missouri. Professor Kearns has authored or coauthored more than 200 papers in pharmacokinetics, biopharmaceutics, and developmental pharmacology.

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