Handbook on Immunosenescence | basic understanding and clinical applications

Tamas Fulop (u. a.)

ISBN 10: 9401777217 / ISBN 13: 9789401777216

Published by Springer Netherland, 2016

About this Item

Handbook on Immunosenescence | basic understanding and clinical applications | Tamas Fulop (u. a.) | Taschenbuch | 2 Taschenbücher | Englisch | 2016 | Springer Netherland | EAN 9789401777216 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.

Seller Inventory # 109583630

Bibliographic Details

• Title: Handbook on Immunosenescence | basic understanding and clinical applications
• Publisher: Springer Netherland
• Publication Date: 2016
• Language: English
• ISBN 10: 9401777217
• ISBN 13: 9789401777216
• Binding: Taschenbuch
• Condition: Neu
• Dimensions: 235W x 155H x 92D millimeters 235 millimeters width by 155 millimeters height by 92 millimeters depth
• Weight: 2558 grams
• Seller catalogs:
  • Bücher

About this title

Synopsis

“Immunosenescence” is an imprecise term used to describe deleterious age-associated changes to immune parameters observed in all mammals studied so far. It represents a rapidly progressing science in the aging field, with a vertiginous volume of new data, knowledge and concepts concerning these changes. We are poised to be in a position to translate these accumulated data into the clinical setting via better understanding of the contribution of immunosenescence to age-associated pathologies, and their prevention by appropriate interventions. This authoritative handbook seeks to encompass the current state of our knowledge on the multitude of those changes to immunity related to aging, with contributions from experts in the research and clinical areas. This book therefore considers methods and models for studying immunosenescence; cellular immunosenescence of T cells, B cells, neutrophils, antigen presenting cells, NK, NKT and stem cells; genetics; mechanisms including receptors and signal transduction; mitochondria; proteasome; cytokines; neuro-endocrine-immune networks; inflammation; thymus; clinical relevance in disease states including infections, autoimmunity, cancer, metabolic syndrome, neurodegenerative diseases, frailty and osteoporosis; modulation by nutrition, lipids, vaccination and the question “can interventions to influence immunosenescence be realistically proposed based on our current state of knowledge?”

Review

From the reviews: “The Handbook on Immunosenescence, a 1,650-page 2-volume encyclopedia on aging research with 78 articles, includes 5 sections ... . Its strength is the broad coverage of aging, the immune system, and diseases of the elderly. For this reason, the Handbook on Immunosenescence is a worthy addition to any medical library.” (Marc E. Weksler, Gerontology, Vol. 56 (3), March, 2010)