Handbook of Multiple Sclerosis

Reporting on the latest advances made in treating multiple sclerosis (MS) and continuing the high standards set by earlier editions, the Handbook of Multiple Sclerosis, Third Edition examines a wide range of topics from etiology to treatment options.

Analyzes recent developments in the natural history, immunopathology, lesion evolution, and therapy affecting MS treatment-including up-to-date research results from experimental therapies with t-cell vaccines, oral myelin, and monoclonal antibodies!

Summarizing previous breakthroughs and pointing the way toward future research, the Handbook of Multiple Sclerosis, Third Edition

provides a historical summary of the disease and examines the epidemiology and genetics of MS, including new evidence for and against an infectious etiology

investigates virus-induced demyelination, emphasizing models such as canine distemper (CDV), corona, visna, and herpes simplex viruses; the semliki forest virus (SFV); and animal models of autoimmune demyelination

notes the role of magnetic resonance imaging (MRI) in diagnosis, prognosis, natural history, and as a guide to therapy

explores the growing evidence for axonal damage as a major cause of disability in MS

summarizes the natural history of MS and delineates factors influencing exacerbations and progression of the disease

assesses current clinical and biological prognostic indicators for accurate diagnoses of MS as opposed to other idiopathic inflammatory demyelinating diseases (IIDDs) and evaluates the growing number of therapies for treating MS

and more!

"International praise for the previous editions... This is a substantial multi-authored text covering all the important aspects of current knowledge on multiple sclerosis.... ...well produced, illustrated and abounds with well-chosen references... "-Journal of Neurology, Neurosurgery and Psychiatry ...a well-written book that describes both classic and recent knowledge about multiple sclerosis. The contributors are outstanding.... ...clearly and comprehensively organized. -Canadian Medical Association Journal ...a Baedeker of multiple sclerosis research, and a guide to the basic neurobiology of the disorder.... ...excellent sections of undeniable general appeal and great practical use. -Annals of Internal Medicine ...most useful to residents and fellows in neurology...to neurologic clinicians, who are interested in comprehensive and current advances...and to both basic and clinical investigators. -Mayo Clinic Proceedings ...helps to understand the links between the actual knowledge...and the therapies that are applicable in patients....This book is useful for neurologists who have a special interest in multiple sclerosis and look for an overview as well as for the rationale for using newly developed therapies. -European Neurology "present[s] the latest information concerning the immunopathology of this disease and new treatment modalities for those cursed with this affliction. highly recommended for all academic health science library collections. "-E-Streams