Handbook of Regenerative Medicine : Stem Cell-based Approach

This handbook comprehensively explores various facets of stem cells in regenerative medicine, highlighting the interdisciplinary nature of the research. It covers the biology, characteristics, and applications of mesenchymal and non-mesenchymal stem cells in diverse medical contexts. The potential for treating radiation injuries, spinal cord injuries, diabetes, aging-related diseases, osteoarthritis, Alzheimer's disease, and oral surgery is thoroughly investigated, engaging bench scientists and professionals from various fields worldwide.

Furthermore, it delves into the potential of neuronal stem cells for neural repair, myoblast implants for Duchenne muscular dystrophy, and immunotherapy using nongenetically modified natural killer cells. Handbook of Regenerative Medicine: Stem Cell-Based Approach also uncovers the possibilities of botanical leads combined with stem cell therapy and explores the role of stem cells in promoting healthy aging and cancer. Additionally, the book sheds light on the role of cancer stem cells, their intricate role in cancer development and chemoresistance, particulary in lungs, gliomas and gynecologic cancers, and their significance as targets in cancer treatment for better prognosis.

The chapters discuss the potential of engineering mesenchymal stem cells for bone regeneration and treating intracerebral hemorrhage. Toward the end, the book elucidates cell-free scaffolding for tissue engineering, adult stem cell disease tropism, and the evolving strategies in regenerative medicine. It is intended for researchers, professionals, and academicians in regenerative medicine, stem cell biology, and medical biotechnology.

Dr. Khawaja Husnain Haider is a Professor of Cellular and Molecular Pharmacology (Stem Cell and Gene Therapy) and Chairman of the Basic Sciences Department (Medical Program) at Sulaiman AlRajhi University. Before his current assignment, he served in several prestigious institutions in various parts of the world. He has also served as Principal Investigator (PI) and Co-PI on multiple National Institute of Health (NIH) funded stem cell research projects. He has been on the editorial boards and invited reviewer panels for several respected international journals. His research focuses on using, either alone or in combination, DNA, miRNAs, and stem cells as “drugs,” a topic that has gained popularity in regenerative medicine. He has extensively published on cellular and sub-cellular preconditioning of stem cells and using their conditioned media for cell-free therapy. He has published nearly 350 book chapters, abstracts, and research papers in various books and leading research journals, including Circulation, Circulation Research, Cardiovascular Research, JCMM, the Journal of Biological Chemistry, Cell Cycle, Basic Research in Cardiology, and Antioxidant Redox Signaling. He has also given numerous presentations and edited ten books covering various facets of stem cells and their applications from drug to drug development.