Hemoglobin : Insights Into Protein Structure, Function, and Evolution

Jay F. Storz

ISBN 10: 0198810695 / ISBN 13: 9780198810698

Published by Oxford University Press (UK), 2019

About this Item

nach der Bestellung gedruckt Neuware - Printed after ordering - The primary aim of this book is to provide a synthesis of our current understanding of hemoglobin function and evolution, and to illustrate how research on one particular family of proteins has provided general insights into mechanisms of protein evolution and biochemical adaptation. In doing so, it will also promote an appreciation of how mechanistic insights into protein function can enrich our understanding of how evolution works. Reciprocally, it highlights how approaches in evolutionary genetics (such as phylogenetic comparative methods and ancestral sequence reconstruction) can be brought to bear on questions about the functional evolution of proteins. This treatise on the functional evolution of hemoglobin illustrates how research on a single, well-chosen model system can enhance our investigative acuity and bring key conceptual questions into especially sharp focus.

Seller Inventory # 9780198810698

Bibliographic Details

• Title: Hemoglobin : Insights Into Protein Structure, Function, and Evolution
• Publisher: Oxford University Press (UK)
• Publication Date: 2019
• Language: English
• ISBN 10: 0198810695
• ISBN 13: 9780198810698
• Binding: Taschenbuch
• Condition: Neu
• Dimensions: 246W x 189H x 14D millimeters 246 millimeters width by 189 millimeters height by 14 millimeters depth
• Weight: 506 grams

About this title

Synopsis

The primary aim of this book is to provide a synthesis of our current understanding of hemoglobin function and evolution, and to illustrate how research on one particular family of proteins has provided general insights into mechanisms of protein evolution and biochemical adaptation. In doing so, it will also promote an appreciation of how mechanistic insights into protein function can enrich our understanding of how evolution works. Reciprocally, it highlights how approaches in evolutionary genetics (such as phylogenetic comparative methods and ancestral sequence reconstruction) can be brought to bear on questions about the functional evolution of proteins. This treatise on the functional evolution of hemoglobin illustrates how research on a single, well-chosen model system can enhance our investigative acuity and bring key conceptual questions into especially sharp focus.

About the Author

Jay F. Storz, Susan J. Rosowski Professor of Biology, School of Biological Sciences, University of Nebraska, USA

Jay Storz is the Susan J. Rosowski Professor of Biology at the University of Nebraska. His research is motivated by questions about mechanisms of protein evolution, gene family evolution, and the genetic basis of biochemical and physiological adaptation. Professor Storz's work is supported by the National Institutes of Health and the National Science Foundation.