High Throughput Analysis for Food Safety

MEETS FSMA REQUIREMENTS WITH THE LATEST ADVANCES IN HIGH-THROUGHPUT SCREENING

High-Throughput Analysis for Food Safety addresses the fundamental concepts involved in the rapid screening for contaminants, including residual veterinary drugs, proteins, metals, hormones, pesticides, and adulterants. Addressing the need for―and requirements of―rapid screening tests, the book includes discussions of regulations and compliance issues from perspectives of both domestic and global industry and government contributors. The latest developments and most common techniques are focused on, with an emphasis on the applicability of both stand-alone mass spectrometry methods and coupled techniques. Beginning with a review of high-throughput analysis basics, the authors conduct a full exploration of mass spectrometry applications allowing readers to:

• Survey GC-MS, LC-MS, stand-alone MS, and tandem MS methods in foodanalysis and contaminant screening
• Review quality control standards, method validation, and ongoing analyticalcontrol
• Examine the current methods used to detect veterinary medicinal productresidues in food, as well as future directionsRecent

Recent incidents around the globe have turned the food industry toward high-throughput analysis, and the Food Safety Modernization Act has made it a legal requirement in the US. This resource provides an in-depth discussion of the latest advances in methods and instrumentation.

PERRY G. WANG, PHD, is a research chemist in the Office of Regulatory Science, CFSAN, US FDA. Prior to joining the FDA, Dr. Wang worked in the pharmaceutical and medical device industries. His expertise in the pharmaceutical field focuses on high-throughput drug analysis by LC-MS/MS. His current research at the FDA includes developing analytical methods for chemical ingredients in cosmetics and personal care products by GC-MS/MS and LC-MS/MS. This book is edited in his private capacity but not as an employee of the FDA.

MARK F. VITHA, PHD, is a professor at Drake University. He is the editor of The Chemical Analysis Series (Wiley) and the co-editor of Interfaces and Interphases in Analytical Chemistry. In 2011, he was awarded the Windsor Professor of Science and the Ronald D. Troyer Research Fellowship.

JOHN F. KAY, PHD, is a chemist and recently retired as the R&D manager at the UK Veterinary Medicines Directorate. For almost 20 years he actively participated in the Codex Alimentarius Committee on Residues of Veterinary Drugs in Food and remains on the JECFA expert roster 2012-2016 for veterinary drug residues. He has held an Honorary Senior Research Fellowship in the Department of Mathematics and Statistics at the University of Strathclyde, Scotland since 2005.