High-Throughput Metabolomics : Methods and Protocols

Angelo D'Alessandro

ISBN 10: 149399235X / ISBN 13: 9781493992355

Published by Springer New York, Springer New York, 2019

About this Item

Druck auf Anfrage Neuware - Printed after ordering - This detailed volume focuses on recent technological, computational, and biostatistical advances in the field of high-throughput metabolomics. Chapters encompass methods, platforms, and analytical strategies for steady state measurements and metabolic flux analysis with stable isotope-labeled tracers, in biological matrices of clinical relevance and model organisms. Mass spectrometry-based or orthogonal methods are discussed, along with computational and statistical methods to address data sparsity in high-throughput metabolomics approaches. As a part of the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and practical, High-Throughput Metabolomics: Methods and Protocols provides tools that can bring about thenext generation of clinical biochemistry in a cost-effective, rigorous fashion, exponentially advancing our capacity to investigate nature while hastening the advent of personalized medicine.

Seller Inventory # 9781493992355

Bibliographic Details

• Title: High-Throughput Metabolomics : Methods and Protocols
• Publisher: Springer New York, Springer New York
• Publication Date: 2019
• Language: English
• ISBN 10: 149399235X
• ISBN 13: 9781493992355
• Binding: Buch
• Condition: Neu
• Dimensions: 260W x 183H x 31D millimeters 260 millimeters width by 183 millimeters height by 31 millimeters depth
• Weight: 1085 grams

About this title

Synopsis

This detailed volume focuses on recent technological, computational, and biostatistical advances in the field of high-throughput metabolomics. Chapters encompass methods, platforms, and analytical strategies for steady state measurements and metabolic flux analysis with stable isotope-labeled tracers, in biological matrices of clinical relevance and model organisms. Mass spectrometry-based or orthogonal methods are discussed, along with computational and statistical methods to address data sparsity in high-throughput metabolomics approaches. As a part of the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. 

Authoritative and practical, High-Throughput Metabolomics: Methods and Protocols provides tools that can bring about thenext generation of clinical biochemistry in a cost-effective, rigorous fashion, exponentially advancing our capacity to investigate nature while hastening the advent of personalized medicine.