Histone and Non-Histone Reversible Acetylation in Development, Aging and Disease

Language: English

Published by Springer, Palgrave Macmillan Jul 2025, 2025

3031914589 / 9783031914584

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Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermanyBuchWeltWeit Ludwig Meier e.K.

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This item is printed on demand - it takes 3-4 days longer - Neuware -This volume explores various aspects of reversible acetylation of histone and non-histone proteins, focusing on their roles in development, ageing and disease progression. It examines the biological consequences of modulating acetylation levels by histone acetyltransferases (HATs) and histone deacetylases (HDACs). Covered are manipulations at multiple levels, from in vitro and in vivo studies to clinical trials and FDA-approved therapies.The book is divided in four parts:Part I provides an overview of post-translational modifications in the context of development, ageing, neurodegenerative and cancer-related diseases. It highlights the role of histone acetylation in higher genome organization and explores the functions of the proteins involved.Part II focuses on the modulation of cytoskeleton-associated proteins through reversible acetylation. It examines how acetylation influences cytoskeletal compartments, thereby regulating cellular structure and function.Part III examines acetylation in the context of development. It describes acetylation as a key regulator of early embryogenesis, influencing chromatin structure and gene expression.Part IV discusses physiological and pathological aspects of histone and non-histone protein acetylation and its modulation by activators and inhibitors.The book is a valuable resource for scientists, clinicians and academic teachers alike. 444 pp. Englisch.

Seller Inventory # 9783031914584

Title
Histone and Non-Histone Reversible Acetylation in Development, Aging and Disease
Author
Marta Halasa
Publisher
Springer, Palgrave Macmillan Jul 2025
Publication year
2025
Condition
Neu
Binding
Buch
Language
English
ISBN 10
3031914589
ISBN 13
9783031914584
Item weight
907 grams
Dimensions
241x160x28 mm

BuchWeltWeit Ludwig Meier e.K.

Bergisch Gladbach, Germany

5-star seller

AbeBooks seller since January 11, 2012

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BuchWeltWeit Ludwig Meier e.K.

Germany