Histone Variants: Methods and Protocols

Orsi, Guillermo A. (Edited by)/ Almouzni, Geneviève (Edited by)

ISBN 10: 1493986627 / ISBN 13: 9781493986620

Published by Humana Press, 2018

About this Item

371 pages. 10.00x7.01x1.10 inches. In Stock. Seller Inventory # x-1493986627

Bibliographic Details

Title: Histone Variants: Methods and Protocols

Publisher: Humana Press

Publication Date: 2018

Binding: Hardcover

Condition: Brand New

About this title

Synopsis:

This volume compiles methodologies used for detailed studies of histone variants, from their basic properties to their functional roles in chromatin and as vectors of epigenetic information. Its four sections cover experimental approaches to probe the biochemistry of histone variants and variant nucleosomes; their dynamics throughout the cell cycle and at specific genomic locations; their functional impact on chromosome organization and genome stability; and their importance in development, disease and evolution. Written in the highly successful Methods in Molecular Biology series format, chapters include lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, illustrations on the expected results, and tips on troubleshooting and avoiding known pitfalls. This anthology brings together contributions from many of the most highly recognized investigators in this community.

Cutting-edge and thorough, Histone Variants: Methods and Protocols is a valuable resource for anyone interested in exploring the experimental and collaborative possibilities in this evolving field.