Horizontal Gene Transfer in the Evolution of Pathogenesis

ISBN 10: 0521862973 / ISBN 13: 9780521862974

Published by Cambridge University Press, 2008

About this Item

pp. 344 Illus.

Seller Inventory # 8371001

Bibliographic Details

• Title: Horizontal Gene Transfer in the Evolution of Pathogenesis
• Publisher: Cambridge University Press
• Publication Date: 2008
• Language: English
• ISBN 10: 0521862973
• ISBN 13: 9780521862974
• Binding: Hardcover
• Condition: New

About this title

Synopsis

Horizontal gene transfer is a major driving force in the evolution of many bacterial pathogens. The development of high-throughput sequencing tools and more sophisticated genomic and proteomic techniques in recent years has resulted in a better understanding of this phenomenon. Written by leading experts in the field, this edited volume is aimed at graduate students and researchers and provides an overview of current knowledge relating to the evolution of microbial pathogenicity. This volume provides an overview of the mechanisms and biological consequences of the genome rearrangements resulting from horizontal gene transfer, in both prokaryotes and eukaryotes, as well as overviews of the key mobile genetic elements involved. Subsequent chapters focus on paradigms for the evolution of important bacterial pathogens, including Salmonella enterica, Streptococcus pneumoniae, and Staphylococcus aureus. The influence of socioeconomic parameters in the dissemination of transferable elements, such as antibiotic resistant genes in bacteria is also discussed.

About the Authors

Michael Hensel is currently Professor of Microbiology and Immunology at the University of Erlangen in Germany.

Herbert Schmidt is currently Professor of Food Microbiology at the University of Hohenheim in Germany.