Image-Guided High-Precision Radiotherapy

This book equips readers with detailed knowledge on the current status of image-guided radiotherapy with photons and particles and highlights issues that need to be addressed in order to further improve treatment outcomes. The opening chapters cover clinical and technical aspects of target volume definition using anatomic (computed tomography and magnetic resonance imaging; MRI) as well as functional (MRI and positron emission tomography) imaging. Up-to-date information is then provided on the full range of image-guided high-precision radiotherapy techniques, including IMRT/VMAT, stereotactic body radiation therapy, MR-guided linear accelerators, MR-guided brachytherapy, and particle therapy. The role of ultrasonography in image-guided radiotherapy is discussed, as are the available means for target volume demarcation and stabilization and adaptive radiation therapy. Finally, outcome evaluation is explored in depth, with a particular focus on the role of multimodality imaging in predicting tumor control and normal tissue toxicity. The authors are experts in different specialties and the book will be of high value for radiation oncologists, medical physicists, radiologists, nuclear medicine physicians, and radiation technicians.

Esther Troost, MD, PhD, is a radiation oncologist, chair of the Department of Radiotherapy and Radiation Oncology of the University Hospital Carl Gustav Carus, professor of image-guided high-precision radiation therapy at the Faculty of Medicine of the Technische Universität Dresden, Germany, and group leader at the Helmholtz-Zentrum Dresden-Rossendorf, Germany. She focuses on incorporating anatomical and functional imaging in radiation treatment planning and early response evaluation for personalised treatment and on exploiting imaging changes as objective measures of tumor response. Professor Troost is a reviewer for numerous international scientific journals, a member of national and international societies, and director of the European Society for Radiotherapy and Oncology (ESTRO) teaching course on “Target volume delineation”.