Inflammation refers to the defensive response of living tissue with vascular system to inflammatory factors and local damage. When your body activates the immune system, it releases inflammatory cells. These cells attack infection from external pathogens, such as bacteria and viruses. Inflammation is a protective mechanism for the body. However, in relation to disease, certain factors can activate an inflammatory responses, such as, bad diet, sedentary lifestyles, environmental factors, etc. Ongoing inflammation, or chronic inflammation can lead to tissue damage and development of diseases. In this Topic, papers are presented in relation to the links between inflammation and disease.

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