Innate Immunity

Language: English

Published by Humana Press, Humana Press Aug 2012, 2012

1468497464 / 9781468497465

Series: Book 8 of 36 - Infectious Disease

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This item is printed on demand - Print on Demand Titel. Neuware -The concept of innate immunity refers to the first-line host defense that serves to limit infection in the early hours after exposure to microorganisms. Recent data have highlighted similarities between pathogen recognition, signaling pathways, and effector mechanisms of innate immunity in Drosophila and mammals, pointing to a common ancestry of these defenses. In addition to its role in the early phase of defense, innate immunity in mammals appears to playa key role in stimulating the subsequent clonal response of adaptive immunity. Recent exciting information has determined that the templates that are laid down in primitive life forms, like flowering plants and insects, form the basic principles of first line host defense that are conserved in mammalian systems. The next frontier in the field is to understand the dynamic adaptive changes that occur as a result of the inter play between host defenses and infectious agents. One emerging theme is that microorganisms are constantly seeking ways to co-opt host defenses. On the other hand, host defense to infection is mediated by the coordinate action of pattern recognition molecules and receptors that, in mammals, are important and probably necessary antecedents to the development of an adaptive immune response. Innate Immunity aims to explore the intersection between host pathogen interactions across an evolutionary spectrum that will inform our understanding of the dynamic interplay between infectious agents and host defense in man.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 424 pp. Englisch.

Seller Inventory # 9781468497465

Title
Innate Immunity
Author
Jules A. Hoffmann
Publisher
Humana Press, Humana Press Aug 2012
Publication year
2012
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
1468497464
ISBN 13
9781468497465
Item weight
793 grams
Dimensions
254x178x23 mm
Series
Book 8 of 36: Infectious Disease

buchversandmimpf2000

Emtmannsberg, BAYE, Germany

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