Integrative transcriptomic analysis of plant co-expression networks: A study of gene function prediction and knowledge transfer between species

Mutwil, Marek

ISBN 10: 3847303163 / ISBN 13: 9783847303169

Published by LAP LAMBERT Academic Publishing, 2011

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Bibliographic Details

• Title: Integrative transcriptomic analysis of plant co-expression networks: A study of gene function prediction and knowledge transfer between species
• Publisher: LAP LAMBERT Academic Publishing
• Publication Date: 2011
• Language: English
• ISBN 10: 3847303163
• ISBN 13: 9783847303169
• Binding: paperback
• Condition: New
• Book Type: book

About this title

Synopsis

Model organisms, such as Arabidopsis, are readily used in basic research due to resource availability and relative speed of data acquisition. A major goal is to transfer the acquired knowledge from these model organisms to species that are of greater importance to our society. However, due to large gene families in plants, the identification of functional equivalents of well characterized Arabidopsis genes in other plants is a non-trivial task, which often returns erroneous or inconclusive results. In this thesis, concepts of utilizing co-expression networks to help infer (i) gene function, (ii) organization of biological processes and (iii) knowledge transfer between species are introduced. An often overlooked fact by bioinformaticians is that a bioinformatic method is as useful as its accessibility. Therefore, majority of the work presented in this thesis was directed on developing freely available, user-friendly web-tools accessible for any biologist.

About the Author

Marek A, Mutwil, PhD: Completed PhD at Potsdam University, Germany. ProjectLeader at Max Planck Institute for Molecular Plant Physiology, Germany.