Integrins in Health and Disease: Key Effectors of Cell-Matrix and Cell-Cell Interactions (eng)
Language: English
Published by Springer, 2024
- Softcover
- New
Seller: Brook Bookstore On Demand, Napoli, NA, ItalyBrook Bookstore On Demand
AbeBooks seller since October 11, 2022
Condition: New
US$ 165.99
Quantity: Over 20 available
Add to basketItem description from seller
Questo è un articolo print on demand.
Seller Inventory # OGUP6XUJQY
- Title
- Integrins in Health and Disease: Key Effectors of Cell-Matrix and Cell-Cell Interactions (eng)
- Author
- Gullberg, Donald
- Publisher
- Springer
- Publication year
- 2024
- Condition
- new
- Binding
- Soft cover
- Language
- English
- ISBN 10
- 3031237838
- ISBN 13
- 9783031237836
- Item weight
- 0.84 kilograms
Integrins are heterodimeric cell surface receptors which anchor cells to different extracellular matrix proteins or act as cell-cell receptors. They play pivotal roles not only across a wide range of physiological processes including tissue morphogenesis, wound healing, and regulation of cell growth, but also in numerous pathological conditions such as autoimmunity, infectious disease, and carcinogenesis.
This book aims to provide readers a summary of the most important integrins and their respective biological functions. Readers will learn about knockout- and animal models to study the functionality of key collagen-, laminin-, and nephronectin-binding integrins. Additionally, the role of integrins in pathological tissue remodeling in joints and in developing and diseased cardiac tissue are discussed. Reviews of the current knowledge of the role of integrins in tissue and tumor fibrosis, angiogenesis and tumor progression are an important part of this work. Finally, the bookdiscusses integrins in the context of the immune system, how to target integrin-ligand interactions with antibodies, and the role of integrins as receptors for bacterial and viral cell invasion.
Both experienced researchers and clinicians, as well as PhD students who wish to study the extracellular matrix and cell adhesion molecules will find “Integrins in Health and Disease - Key Effectors of Cell-Matrix and Cell-Cell Interactions” authoritative, easily accessible, and vastly informative.
The series Biology of Extracellular Matrix is published in collaboration with the American Society for Matrix Biology and the International Society for Matrix Biology.
"Synopsis" may belong to another edition of this title.
About the Author
After having studied biochemistry at the University of Tübingen, Johannes A. Eblegained an intense training on extracellular matrix and collagen-binding integrins during his doctorate thesis at the Max Planck-Institute of Biochemistry in Martinsried close to Munich. In 1994, he gained his doctorate degree from the Ludwig Maximilians-University, Munich, under the Prof. Dr. Klaus Kühn’s supervision. During 1995-1998, he intensified his knowledge of integrins under Prof. Martin Hemler’s supervision at the Dana Faber-Cancer Institute of Harvard Medical School in Boston, where he developed the technique of recombinant expression of soluble integrins, especially of the laminin-332-binding ITGA3 integrin. After his return to Germany, he habilitated at the University of Münster in 2004. In 2008, he was appointed to a professorship of vascular matrix biology at the University of Frankfurt within the Excellence Cluster Cardio-Pulmonary System. Since 2014, he heads the Institute of Physiological Chemistry and Pathobiochemistry of the University of Münster. Although his scientific focus still pivots around integrins, his view on cell adhesion and migration has widened to integrin agonists and antagonists, the former being recombinant integrin-binding mini-collagen and mini-laminin-332, the latter being integrin-blocking snake venom toxins. Moreover, redox regulation of integrins and cell-matrix contacts is also included in his research portfolio.
"About the title" may belong to another edition of this title.
Brook Bookstore On Demand
Napoli, NA, Italy
AbeBooks seller since October 11, 2022
Shipping rates from Italy to U.S.A.
| Item | 25 to 40 business days | 60 to 60 business days |
|---|---|---|
| First item | US$ 9.06 | US$ 578.81 |
Payment methods
Store description
Account dedicated to Print on Demand titles. Brook Bookstore offers a wide selection of books with a continuously updated catalog and fast shipments all over the world. We hold distribution rights with all of the publishers we promote and are in continuous search of new interesting titles to propose to our customers. We are part of Brandon Group SRL (an Italian company) and all of the orders are shipped from Europe. Depending on availability orders will be picked from our different warehouses. CONTACT US If you have any questions please do not hesitate to contact us sending a message to our store. We have a well prepared customer service team who will be happy to assist you. Our working hours are from Monday to Friday from 9:30 to 18:30 (CET, UTC +1) so messages received during the weekends might be responded with a slight delay but we guarantee you will get back to you as soon as possible. RETURNS If you want to return your order, please submit your request through Abebooks platform. Returns requests are managed case by case by our team and always in line with Abebooks policies: AbeBooks’ Return Policy guarantees that you can return any book for a refund within 30 days, when the return is due to an error on the bookseller’s part. When the motive of the return is not due to an error of the seller it is up to Brook Bookstore to accept the return or else after studying the case. CANCELLATION You can send a cancellation request to our customer service team while the package has not yet been shipped. After that we cannot ensure we can retrieve the parcel but we suggest you to get in touch with us in order to verify the case. INVOICE You can request the invoice to be issued together with the shipment of the order or, at the latest, in the same month of the shipment. …
Specialty
Print on DemandSeller's business information
Brandon Group S.R.L.
Via Vannella Gaetani 27, Brandon Group
Napoli, NA Italy 80121
Terms of sale
Account dedicated to Print on Demand titles.
CANCELLATION
You can send a cancellation request from the order page while the package has not yet been shipped. After that we cannot ensure we can retrieve the parcel but we suggest you to get in touch with us in order to verify the case.
INVOICE
You can request the invoice to be issued together with the shipment of the order or, at the latest, in the same month of the shipment.
RETURNS
If you want to return your order, please contact us for authorization or place a request on the order page. Orders returned without authorization may not be credited.
If your order presents damages or any other issue on arrival we must be advised of this within 14 days of delivery in order to find the most suitable solution for you.
Returns for Brook Bookstore (Brandon Group SRL) are only accepted in the following addresses:
Return address in the United Kingdom:
MHI
(c/o BR Books)
82 Feeder Road
Bristol
BS2 0TQ
UK
Return address in Italy (for all EU countries):
Brandon Group c/o TWS
Via Trento, 9
20067 Tribiano (MI) – Italy
Return address in Japan:
Brandon Group JP
c/o Windows, Inc.
Mr. Jiro Asami
2-12-7-504 Oshiage, Sumida-ku
Tokyo 131-0045 Japan
Return address in the USA:
TruLogic- EZI - Brook Bookstore
5401 NW 72nd ave
MIami FL 33166-4941
Return address in Australia:
Active - Ezi - - Brook Bookstore
2/2-4 Federation Way,
Moorabbin Airport
Mentone, 3194
Victoria
AUSTRALIA
Return address in Canada:
No3rd - Ezi - - Brook Bookstore
520 Ave Lepine
Dorval QC H9P 2V6
CANADA
Return address in Mexico:
Chronos - EZI - Brook Bookstore
Calle Duba 112
Parque industrial Logistik II
79526 Villa de Reyes
San Luis Potosi
*For returns from other areas please contact us in order to provide further assistance.