Synopsis
Interest in interleukin-1 (IL-1) has increased dramatically over the last decade, but has been largely restricted to immunologists, cell biologists and those studying inflammation and cancer. However, it has recently been recognized that the brain directly controls or modulates many aspects of immune function, while molecules classically associated with the immune system, such as interleukin-1, are synthesised within the brain and act directly on the central nervous system to modify local and systemic functions. Thus, this topic is relatively new to neurobiologists, and this book is the first comprehensive description of current knowledge on interleukin-1 in the brain, including its location, synthesis and receptors, actions on behaviour, fever, metabolism, neuroendocrine function, electrical activity of the brain, nerve growth factor, and relationship to clinical indications. The book is organised into three sections. The first reviews the dat
Review
1993 The quality of the chapters is generally very good, and each contains a rather extensive reference list that would be of use to anyone with an active interest in the field...provides a single-source overview of the field. -- Emmett T. Cunningham, Immunology Today
1994 Certainly, the editors did not mean to compile extensive reviews but rather set some highlights touching on major aspects in this field of research and encouraging the interested reader to dig for more details in specialized journals. This "appetite" is nourished, in particular, by the smart combination of reviews decorated with a few recent results from each contributors' own laboratories. In this way, it was possible to reasonably price the book and make it appealing for both the interested scientist and the insider. It is another milestone in the successful series of Pergamon studies in neuroscience. -- Peter J. Gebicke-Haerter, Neurochemistry International
Certainly, the editors did not mean to compile extensive reviews but rather set some highlights touching on major aspects in this field of research and encouraging the interested reader to dig for more details in specialized journals. This "appetite" is nourished, in particular, by the smart combination of reviews decorated with a few recent results from each contributors' own laboratories. In this way, it was possible to reasonably price the book and make it appealing for both the interested scientist and the insider. It is another milestone in the successful series of Pergamon studies in neuroscience. -- Peter J. Gebicke-Haerter, Neurochemistry International, 1994
The quality of the chapters is generally very good, and each contains a rather extensive reference list that would be of use to anyone with an active interest in the field...provides a single-source overview of the field. -- Emmett T. Cunningham, Immunology Today, 1993
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