The Intervertebral Disc: Molecular and Structural Studies of the Disc in Health and Disease

ISBN 10: 370911943X / ISBN 13: 9783709119433

Published by Springer, 2016

About this Item

PRINT ON DEMAND pp. 456.

Seller Inventory # 18378097308

Bibliographic Details

• Title: The Intervertebral Disc: Molecular and Structural Studies of the Disc in Health and Disease
• Publisher: Springer
• Publication Date: 2016
• Language: English
• ISBN 10: 370911943X
• ISBN 13: 9783709119433
• Binding: Soft cover
• Condition: New

About this title

Synopsis

The intervertebral disc is a complex structure that separates opposing vertebrae, permits a wide range of motion, and accommodates high biomechanical forces. Disc degeneration leads to a loss of function and is often associated with excruciating pain.

Written by leading scientists and clinicians,  the first part of the book provides a review of the basic biology of the disc in health and disease. The second part considers strategies to mitigate the effects of disc degeneration and discusses the possibility of engineering replacement tissues. The final section is devoted to approaches to model normal development and elucidate the pathogenesis of degenerative disc disease using animal, organ and cell culture techniques. 

The book bridges the gap between the basic and clinical sciences; the target audience includes basic scientists, orthopaedists and neurologists, while at the same time appealing to the needs of  graduate students, medical students, interns and fellows.

About the Author

Irving M. Shapiro BDS, PhD

Makarand Risbud, Ph.D.

Division of Orthopaedic Research, Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA, USA