Intrinsically Disordered Proteins: Dynamics, Binding, and Function thoroughly examines and ties together the fundamental biochemical functions of intrinsically disordered proteins (IDPs) and intrinsically disordered regions (IDRs), including signaling, binding, and regulation, with the methodology for study and the associated pathways for drug design and therapeutic intervention. The role of new mechanistic, computational, and experimental approaches in IDP study are explored in depth, with methods for the characterization of IDP dynamics; models, simulations, and mechanisms of IDP and IDR binding; and biological and medical implications of IDP dynamics prominently featured. Written and edited by leading scientists in the field, this book explores groundbreaking areas such as ensemble descriptions of IDPs and IDRs, single-molecule studies of IDPs and IDRs, IDPs and IDRs in membraneless organelles, and molecular mechanisms of fibrillation of IDPs.

Intrinsically Disordered Proteins provides students and researchers in biochemistry, molecular biology, and applied microbiology with a comprehensive and updated discussion of the complex dynamics of IDPs and IDRs.

Provides in-depth discussion of fundamental IDP and IDR dynamics, function, and binding, with mechanistic insight to support new drug development
Describes the role of new computational and experimental approaches in characterizing the binding of IDPs to their functional targets
Features chapter contributions from international experts in IDP and IDR biochemical function and methods of study

About the Author

Dr. Nicola Salvi is a research scientist at the Institut de Biologie Structurale in Grenoble, France. After receiving his doctorate from the Ecole Polytechnique F�d�rale de Lausanne, Switzerland, under the supervision of Geoffrey Bodenhausen, he held a postdoctoral appointment at Harvard Medical School. Dr. Salvi is an expert in characterizing protein dynamics using nuclear magnetic resonance spectroscopy. He developed hybrid approaches in which spectroscopic evidence on intrinsically disordered proteins (IDPs) is combined with molecular dynamics simulation to obtain insights into the functional dynamics of IDPs. Dr. Salvi’s studies led to identifying mechanistic paradigms of IDP motions, with important implications for our understanding of their function.

"About this title" may belong to another edition of this title.

Store Description

Account dedicated to Print on Demand titles. Brook Bookstore offers a wide selection of books with a continuously updated catalog and fast shipments all over the world. We hold distribution rights with all of the publishers we promote and are in continuous search of new interesting titles to propose to our customers. We are part of Brandon Group SRL (an Italian company) and all of the orders are shipped from Europe. Depending on availability orders will be picked from our different warehouses. CONTACT US If you have any questions please do not hesitate to contact us sending a message to our store. We have a well prepared customer service team who will be happy to assist you. Our working hours are from Monday to Friday from 9:30 to 18:30 (CET, UTC +1) so messages received during the weekends might be responded with a slight delay but we guarantee you will get back to you as soon as possible. RETURNS If you want to return your order, please submit your request through Abebooks platform. Returns requests are managed case by case by our team and always in line with Abebooks policies: AbeBooks? Return Policy guarantees that you can return any book for a refund within 30 days, when the return is due to an error on the bookseller?s part. When the motive of the return is not due to an error of the seller it is up to Brook Bookstore to accept the return or else after studying the case. CANCELLATION You can send a cancellation request to our customer service team while the package has not yet been shipped. After that we cannot ensure we can retrieve the parcel but we suggest you to get in touch with us in order to verify the case. INVOICE You can request the invoice to be issued together with the shipment of the order or, at the latest, in the same month of the shipment.

Visit Seller's Storefront

Seller's business information

Brandon Group S.R.L.
Via Vannella Gaetani 27, Brandon Group, Napoli, NA, 80121, Italy

Sale & Shipping Terms

Terms of Sale

Account dedicated to Print on Demand titles.

CANCELLATION
You can send a cancellation request from the order page while the package has not yet been shipped. After that we cannot ensure we can retrieve the parcel but we suggest you to get in touch with us in order to verify the case.

INVOICE
You can request the invoice to be issued together with the shipment of the order or, at the latest, in the same month of the shipment.

RETURNS
If you want to return your order, please contact us for authoriz...

More Information

Shipping Terms

Shipping rates from Italy to U.S.A.

Shipping rates from Italy to U.S.A.
Order quantity	25 to 40 business days	60 to 60 business days
First item	US$ 9.22	US$ 588.87

Delivery times are set by sellers and vary by carrier and location. Orders passing through Customs may face delays and buyers are responsible for any associated duties or fees. Sellers may contact you regarding additional charges to cover any increased costs to ship your items.