Introduction to Bioinformatics

Suhasini Bhatnagar

Published by S R Scientific, Agra, 2009

About this Item

Contents 1. Essentials of computer i. Introduction to bioinformatics. ii. Applications of bioinformatics. iii. Networking. iv. Introduction to SQL. 2. Bioprogramming i. C++. ii. Bio Perl. iii. Biojava. 3. Softwares and applications i. Clustal. W. ii. Ras Mol. iii. Molscript. iv. Tree view. v. Alscript. vi. Phylip. 4. Databases i. What is a database. ii. Different types of biological databases. iii. Database similarity searches. iv. Sqlj and Sqi *plus. v. Internet based biological databases. vi. Sequence databases. vii. Data mining and visualisation. 5. Sequence alignments i. Dot plots. ii. Needleman Wunsch. iii. Smith waterman. iv. Similarity matrices and Penalties. v. Multiple sequence alignments scoring mathematical optimal and heuristic methods. 6. Sequence searches in biological databases i. BLAST 1 and BLAST 2. ii. FASTA. iii. PHI and PSI BLAST. iv. Phylogenetic trees distance based phylogenies UPGMA and neighbour joining. v. Character based phylogenies parsimony trees and maximum likelihood method. 7. Genomics and genome analysis i. Data analysis. ii. Gene prediction (prokaryotic eukaryotic promoter prediction transcription factor binding sites). iii. Protein function prediction. iv. Genome comparison and pattern matching. v. Substitution patterns. 8. Proteomics and proteome i. Visualisation and modeling with secondary structure prediction. ii. Localization/hydrophobicity and analysis of domains. iii. 3D alignment and folding classes with families and domains. iv. DNA chips. v. Normalisation of data/statistical evaluation. 9. Drug designing i. Stabilisation and substrate specificity. ii. Rationale for drug design. iii. Humanisation of antibodies. v. Protein/protein docking and protein/ligand docking. 740 pp.

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Bibliographic Details

• Title: Introduction to Bioinformatics
• Publisher: S R Scientific, Agra
• Publication Date: 2009
• Binding: Hardbound
• Edition: New
• Condition: As New