Investigation of Enzyme activity of E.Coli. in Adverse Condition | Challenges for survival in Acidic Condition

Vivek Jain (u. a.)

ISBN 10: 3639311922 / ISBN 13: 9783639311921

Published by VDM Verlag Dr. Müller, 2010

About this Item

Investigation of Enzyme activity of [.]. in Adverse Condition | Challenges for survival in Acidic Condition | Vivek Jain (u. a.) | Taschenbuch | Englisch | VDM Verlag Dr. Müller | EAN 9783639311921 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu.

Seller Inventory # 107220220

Bibliographic Details

• Title: Investigation of Enzyme activity of E.Coli. in Adverse Condition | Challenges for survival in Acidic Condition
• Publisher: VDM Verlag Dr. Müller
• Publication Date: 2010
• Language: English
• ISBN 10: 3639311922
• ISBN 13: 9783639311921
• Binding: Taschenbuch
• Condition: Neu
• Seller catalogs:
  • Bücher

About this title

Synopsis

The objective of this work is to study the response of this neutrophile in an acidic environment with respect to the activities of isocitrate, malate, succinate and G-6-PD on being coupled to the electron transport chain. E.coli have an optimum pH range of 6 to7 for growth and survival and are hence,called neutrophiles. When challenged by low pH, protons enter the cytoplasm; as a result mechanisms are required to alleviate the effects of lowered cytoplasmic pH. This study highlights new insights into activities of isocitrate, succinate, malate and G-6-PD, coupled to the electron transport chain by the reducing power, as yet another system possessed by E.coli as an armor against harsh acidic environments. The activities of dehydrogenases in acid shocked cells were monitored at intervals of 1, 2, 3 and 4 h at different pH and then compared with their activities at pH 7 (taken as control). Acid stressed microorganisms are an economically important group. Acid stable enzymes with applications as lubricants and catalysts. Improvement of strains can be done by studying the acid tolerance of microorganisms in fermentation broth to increase product yield.

About the Author

M.Pharm.Pharmacology:Studied at Punjabi University Patiala. Assistant Professor at Banasthali University,Rajasthan. He has qualified GATE 2006 conducted by IIT.Area of interest is pre- clinical & clinical study on Neuropathy & Cardiovascular disorder. He is the founder of an organization "Pharmacophore Solutions" & a website www.gpatindia.com