Neuware - Both an excess and a shortage of iron causes serious diseases. This book focuses on filling the gap in chemical understanding and our real life by providing fundamental information on genetics, drugs and environmental health.

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Bibliographic Details

Title: Iron in Biology : Molecular Structures, Cellular Processes and Living Systems
Publisher: RSC Publishing Jun 2025
Publication Date: 2025
Language: English
ISBN 10: 183767440X
ISBN 13: 9781837674404
Binding: Buch
Condition: Neu
Dimensions: 236 millimeters width by 157 millimeters height by 25 millimeters depth
Weight: 703 grams

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Synopsis

Heavy metals essential to organisms are termed “biometals”. Bio-inorganic chemistry deals with the functions of biometals in vivo at an atomic to molecular level, while cellular regulation of biometals such as absorption and transport has been investigated in cell biology. Although these research fields are independently developed and matured, interdisciplinary information across these fields is required for a comprehensive understanding of the roles of biometals at atomic to molecular, cellular and organism levels.

This book focuses on iron (Fe) in cells, since it is the most abundant metal in living system and is involved in a variety of physiological events such as enzymatic reactions as catalysts and signal transduction. Both excess and shortage of iron cause serious diseases such as anaemia, cancer and neuronal degeneration. The cellular systems consisting of many specific proteins strictly control the iron contents through the iron dynamics in cells including absorption, sensing, storage, transport and usage.

Resulting from a 5-year project on Integrated Biometal Science in Japan, this book not only documents the latest research but also fills a gap between chemical understanding and our real life, by providing fundamental ideas on genetics, drugs and environmental health.

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