Kinase Screening and Profiling | Methods and Protocols

Hicham Zegzouti (u. a.)

ISBN 10: 1493930729 / ISBN 13: 9781493930722

Published by Humana, 2015

About this Item

Kinase Screening and Profiling | Methods and Protocols | Hicham Zegzouti (u. a.) | Buch | x | Englisch | 2015 | Humana | EAN 9781493930722 | Verantwortliche Person für die EU: Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu Print on Demand.

Seller Inventory # 104617147

Bibliographic Details

• Title: Kinase Screening and Profiling | Methods and Protocols
• Publisher: Humana
• Publication Date: 2015
• Language: English
• ISBN 10: 1493930729
• ISBN 13: 9781493930722
• Binding: Buch
• Condition: Neu
• Dimensions: 260W x 183H x 18D millimeters 260 millimeters width by 183 millimeters height by 18 millimeters depth
• Weight: 702 grams
• Seller catalogs:
  • Bücher

About this title

Synopsis

This volume focuses on screening and profiling kinase inhibitors or activators. Chapters in this book cover several facets of the drug discovery processes starting with target identification, and assay development and screening chemical libraries for hit identification and lead optimization. The profiling portion of Kinase Screening and Profiling: Methods and Protocols discusses several strategies and techniques that are required to minimize off target hits and reduce cellular toxicities that are caused by liability kinases. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Timely and authoritative, Kinase Screening and Profiling: Methods and Protocols, will benefit scientists and researchers who are interested in exploring the role of kinases in academic, as well as pharmaceutical research.