LIVER METABOLISM AND FATTY LIVER DISEASE (HB 2015)

Nonalcoholic fatty liver disease is one of the most common liver diseases worldwide affecting patients from all ages, races, and ethnic backgrounds. It comprises a spectrum of hepatic pathology ranging from simple steatosis, in which there is an increase of fat accumulation in hepatocytes, to nonalcoholic steatohepatitis and cirrhosis. The significant prevalence of this disease―between 15 and 45 percent of the general population―means that it contributes to an increased burden of ill health both today and in the future.

Liver Metabolism and Fatty Liver Disease addresses the current understanding of the development of nonalcoholic fatty liver disease as well as the clinical aspects of the disease by examining the current knowledge surrounding metabolism in the liver. The book discusses various topics including the involvement of oxidative stress, metabolic effects, and inflammation as well as the effect of nutrition on the development and progression of the disease.

Oren Tirosh is an associate professor at the School of Nutrition Science in the Institute of Biochemistry, Food Science and Nutrition at The Hebrew University of Jerusalem. He received his PhD from the School of Pharmacy at The Hebrew University of Jerusalem and completed a postdoctoral fellowship at the University of California, Berkeley. Dr. Tirosh is a lifetime honorary member in the Oxygen Club of California and is active in the board of The Israel Society for Oxygen and Free Radical Research. His research interests include nitric oxide and redox biology, oxidative stress and liver pathology, and lipid metabolism under liver disease conditions.