Lectin Conjugated Gastro-Retentive Delivery System : Gastro-Retentive Multiparticulate Delivery System of Clarithromycin for the Effective Treatment of Helicobacter Pylori

Language: English

Published by LAP Lambert Academic Publishing, 2012

3659213772 / 9783659213779

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Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH

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nach der Bestellung gedruckt Neuware - Printed after ordering - An optimized Ethylcellulose microspheres of Clarithromycin were successfully prepared using emulsion/ solvent evaporation method and Con-A was successfully attached to the microspheres using carbodiimide method. Attachment of lectin to the Ethylcellulose microspheres significantly increased the mucoadhesiveness and also controls the release of Clarithromycin in simulated GI fluids. Conjugation aggregation assay suggesting that the lectin can be able to target in the treatment of Helicobacter pylori infection in peptic ulcer disease. Gamma scintigraphy study suggesting that Con-A lectin conjugated Ethylcellulose microspheres have gained considerable attention due to their ability to adhere to the mucus layer, as well as to release the drug in a controlled manner. It is concluded that designed targeted delivery system could possibly increases the bioavailability of Clarithromycin and treated the gastric ulcer in an effective manner.…

Seller Inventory # 9783659213779

Title
Lectin Conjugated Gastro-Retentive Delivery System : Gastro-Retentive Multiparticulate Delivery System of Clarithromycin for the Effective Treatment of Helicobacter Pylori
Author
Sunil K. Jain
Publisher
LAP Lambert Academic Publishing
Publication year
2012
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
3659213772
ISBN 13
9783659213779
Item weight
136 grams
Dimensions
22.00x15.00x0.40 cm

AHA-BUCH GmbH

Einbeck, Germany

5-star seller

AbeBooks seller since August 14, 2006

Shipping rates from Germany to U.S.A.

Item7 to 10 business days5 to 7 business days
First itemUS$ 39.05US$ 50.21
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