Lesser Harms: The Morality of Risk in Medical Research (Morality and Society Series)

Sydney A. Halpern

ISBN 10: 0226314510 / ISBN 13: 9780226314518

Published by University of Chicago Press, 2004

About this Item

Overall, very good condition. Research physicians face intractable dilemmas when they consider introducing new medical procedures. Innovations carry the promise of preventing or curing life-threatening diseases, but they can also lead to injury or even death. How have clinical scientists made high-stakes decisions about undertaking human tests of new medical treatments? In Lesser Harms, Sydney Halpern explores this issue as she examines vaccine trials in America during the early and mid-twentieth century. Today's scientists follow federal guidelines for research on human subjects developed during the 1960s and 1970s. But long before these government regulations, medical investigators observed informal rules when conducting human research. They insisted that the dangers of natural disease should outweigh the risks of a medical intervention, and they struggled to accurately assess the relative hazards. Halpern explores this logic of risk in immunization controversies extending as far back as the eighteenth century. Then, focusing on the period between 1930 and 1960, she shows how research physicians and their sponsors debated the moral quandaries involved in moving vaccine use from the laboratory to the clinic. This probing work vividly describes the efforts of clinical investigators to balance the benefits and dangers of untested vaccines, to respond to popular sentiment about medical hazards, and to strategically present risk laden research to sponsors and the public. ,ÄúConcise and extremely well-written. . . . A fascinating synthesis of sociology, history, and institutional theory.,Äù,ÄîSamuel C. Blackman, Journal of the American Medical Association.

Seller Inventory # 1148

Bibliographic Details

• Title: Lesser Harms: The Morality of Risk in Medical Research (Morality and Society Series)
• Publisher: University of Chicago Press
• Publication Date: 2004
• Language: English
• ISBN 10: 0226314510
• ISBN 13: 9780226314518
• Binding: Hardcover
• Condition: Very Good
• Weight: 1360 grams

About this title

Synopsis

Research physicians face intractable dilemmas when they consider introducing new medical procedures. Innovations carry the promise of preventing or curing life-threatening diseases, but they can also lead to injury or even death. How have clinical scientists made high-stakes decisions about undertaking human tests of new medical treatments? In Lesser Harms, Sydney Halpern explores this issue as she examines vaccine trials in America during the early and mid-twentieth century.

Today's scientists follow federal guidelines for research on human subjects developed during the 1960s and 1970s. But long before these government regulations, medical investigators observed informal rules when conducting human research. They insisted that the dangers of natural disease should outweigh the risks of a medical intervention, and they struggled to accurately assess the relative hazards. Halpern explores this logic of risk in immunization controversies extending as far back as the eighteenth century. Then, focusing on the period between 1930 and 1960, she shows how research physicians and their sponsors debated the moral quandaries involved in moving vaccine use from the laboratory to the clinic.

This probing work vividly describes the efforts of clinical investigators to balance the benefits and dangers of untested vaccines, to respond to popular sentiment about medical hazards, and to strategically present risk laden research to sponsors and the public.


“Concise and extremely well-written. . . . A fascinating synthesis of sociology, history, and institutional theory.”—Samuel C. Blackman, Journal of the American Medical Association

About the Author

Sydney A. Halpern is professor of sociology and medical humanities at the University of Illinois at Chicago. She is the author of American Pediatrics: The Social Dynamics of Professionalism, 1880–1920.